Development Level

Tchem 6 | 1,598
Tbio 1 | 11,445

IMPC Phenotype

abnormal lens morphology 1 | 81
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
Cancer 4 | 2,499
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
adult high grade glioma 3 | 3,801
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Cardiomyopathies 2 | 110
Cholestasis 2 | 155
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
posterior fossa group A ependymoma 2 | 468
Abnormality of the metaphyses 1 | 48
Abnormally-shaped vertebrae 1 | 31
Absent/hypoplastic paranasal sinuses 1 | 5
Acquired scoliosis 1 | 281
Advanced bone age 1 | 35
Agenesis of teeth 1 | 21
Alzheimer's disease 1 | 658
Arthritis 1 | 290
Attention deficit hyperactivity disorder 1 | 278
Blastic phase chronic myeloid leukemia 1 | 58
Brain disease 1 | 96
Byzanthine arch palate 1 | 194
Cholestasis, Extrahepatic 1 | 25
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Colonic Neoplasms 1 | 142
Conductive hearing loss 1 | 123
Congenital sensorineural hearing loss 1 | 12
Craniofacial hyperostosis 1 | 11
Curvature of spine 1 | 282
Dental abnormalities 1 | 60
Depressive Symptoms 1 | 28
Disease Progression 1 | 136
Disorder of eye 1 | 27
Downward slant of palpebral fissure 1 | 158
Drug-induced depressive state 1 | 14
Edema 1 | 81
Endometriosis 1 | 540
Eye Abnormalities 1 | 35
Flexion contracture of proximal interphalangeal joint 1 | 75
Freckles 1 | 33
Frontometaphyseal dysplasia 1 | 2
Fused cervical vertebrae 1 | 5
Gaucher disease type 1 1 | 180
Hamman-Rich syndrome 1 | 34
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypersensitivity 1 | 63
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Hypoplasia of muscle 1 | 5
Joint stiffness 1 | 84
Liver neoplasms 1 | 130
Long fingers 1 | 9
Lung Neoplasms 1 | 232
Lung disease 1 | 142
Marijuana Abuse 1 | 31
Mitral Regurgitation, Conductive Deafness, and Fusion of Cervical Vertebrae and of Carpal and Tarsal Bones 1 | 1
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Multiple Sclerosis 1 | 540
Myocardial Ischemia 1 | 169
Neoplasms 1 | 63
Parkinson's disease 1 | 392
Patellar tendinitis 1 | 2
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Posterior vertebral hypoplasia 1 | 3
Prominent supraorbital ridges 1 | 19
Reduced number of teeth 1 | 21
Sensorineural Hearing Loss (disorder) 1 | 284
Short thumb terminal phalanx 1 | 5
Synostosis of carpal bones 1 | 9
Tooth Abnormalities 1 | 69
Ulnar deviation of the fingers 1 | 21
Vascular disease 1 | 319
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
atypical teratoid/rhabdoid tumor 1 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
axial spondyloarthropathy 1 | 28
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dermatomyositis 1 | 966
inflammatory breast cancer 1 | 286
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
progressive supranuclear palsy 1 | 676
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Kinase 6 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Cyclic AMP-dependent transcription factor ATF-2 ATF2 Tbio Transcription Factor -2.23104 170.7 1819
Dual specificity mitogen-activated protein kinase kinase 6 MAP2K6 Tchem Kinase -2.01763 74.4 636
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.63128 394.0 648
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.36007 2240.8 1574
Mitogen-activated protein kinase 11 MAPK11 Tchem Kinase -2.06160 98.6 336