Development Level

Tchem 10 | 1,598
Tclin 2 | 613
Tbio 1 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278

Disease

Carcinoma 11 | 11,493
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
lung cancer 7 | 4,740
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
Kidney cancer 4 | 2,613
Acquired scoliosis 3 | 281
Astrocytoma, Pilocytic 3 | 3,081
Byzanthine arch palate 3 | 194
Cardiofaciocutaneous syndrome 3 | 15
Costello Syndrome 3 | 17
Curvature of spine 3 | 282
Downward slant of palpebral fissure 3 | 158
Noonan syndrome 3 | 34
Orbital separation excessive 3 | 244
Short stature 3 | 531
Vascular disease 3 | 319
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of vision 2 | 40
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Atrial Septal Defects 2 | 85
Big calvaria 2 | 147
Blastic phase chronic myeloid leukemia 2 | 58
Blepharoptosis 2 | 231
Brittle hair 2 | 25
Cardiomyopathies 2 | 110
Cardiomyopathy 2 | 116
Cholestasis 2 | 155
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Coarse facial features 2 | 108
Concave bridge of nose 2 | 195
Depressed cheekbone 2 | 22
Depressed nasal root/bridge 2 | 195
Dry skin 2 | 75
Electroencephalogram abnormal 2 | 101
Erdheim-Chester disease 2 | 7
Failure to thrive in infancy 2 | 32
Fine hair 2 | 42
Flattening of the zygomatic bone 2 | 22
Fractured hair 2 | 25
Fragile hair 2 | 25
Frontal bossing 2 | 157
Hamman-Rich syndrome 2 | 34
Hemangioma, Cavernous 2 | 20
High forehead 2 | 102
Hyperhidrosis disorder 2 | 81
Hypertrophic Cardiomyopathy 2 | 117
Hypoplasia of the zygomatic bone 2 | 22
Hypotrophic cheekbone 2 | 22
Ichthyoses 2 | 41
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased sweating 2 | 81
LEOPARD syndrome 2 | 20
Langerhans-cell histiocytosis 2 | 12
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Long philtrum 2 | 137
Low posterior hairline 2 | 52
Lung Neoplasms 2 | 232
Macrotia 2 | 87
Melanoma 2 | 711
Myopia 2 | 176
Palmoplantar keratosis 2 | 74
Pectus excavatum 2 | 100
Premature Birth 2 | 77
Premature birth of newborn 2 | 67
Pulmonary Stenosis 2 | 45
Reduced tensile strength of hair 2 | 25
Senile lentigo 2 | 10
Sensorineural Hearing Loss (disorder) 2 | 284
Short nose 2 | 132
Skin hyperelastic 2 | 32
Small cheekbone 2 | 22
Sparse hair 2 | 59
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Sweating 2 | 81
Tall forehead 2 | 102
Thickened facial skin with coarse facial features 2 | 108
Thin, sparse hair 2 | 59
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38
Xerosis 2 | 75
posterior fossa group A ependymoma 2 | 468

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Kinase 12 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

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