Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating insulin ... 1 | 76
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased mean corpuscular vol... 1 | 92
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Cancer 12 | 2,499
ovarian cancer 12 | 8,520
Carcinoma 9 | 11,493
glioblastoma 9 | 5,792
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
osteosarcoma 7 | 7,950
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Hypercalcemia 5 | 59
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
Abdominal pain, episodic 4 | 9
Acromegaly 4 | 51
Adrenal cortical adenoma 4 | 19
Angiofibroma 4 | 7
Astrocytoma, Pilocytic 4 | 3,081
Diarrhea 4 | 253
Esophagitis 4 | 35
Growth hormone excess 4 | 14
Hyperinsulinaemic hypoglycaemia 4 | 16
Hyperinsulinemia, fasting 4 | 7
Hyperparathyroidism 4 | 48
Increased serum parathyroid hormone 4 | 14
Insulinoma 4 | 24
Melanoma 4 | 711
Multiple Endocrine Neoplasia Type 1 4 | 29
Non-Functioning Pituitary Gland Neoplasm 4 | 6
Parathyroid Adenoma 4 | 19
Parathyroid hyperplasia 4 | 6
Peptic Ulcer 4 | 27
Pituitary growth hormone cell adenoma 4 | 8
Prolactinoma 4 | 11
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
Subcutaneous lipomas 4 | 9
Thyroid Gland Follicular Adenoma 4 | 9
Zollinger-Ellison syndrome 4 | 18
ductal carcinoma in situ 4 | 1,745
intermittent abdominal pain 4 | 9
malignant mesothelioma 4 | 3,232
medulloblastoma 4 | 720
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Adenoma 3 | 167
Carney complex 3 | 25
Kidney cancer 3 | 2,613
Lung Neoplasms 3 | 232
Parkinson's disease 3 | 392
Short stature 3 | 531
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
Abnormality of the lymphatic system 2 | 14
Amyotrophic lateral sclerosis 2 | 451
Cardiomegaly 2 | 116
Cholangiocarcinoma 2 | 35
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dry skin 2 | 75
Duchenne muscular dystrophy 2 | 601
Freckles 2 | 33
Frontal bossing 2 | 157
Glaucoma 2 | 239
Hair shaft abnormalities 2 | 30
Hereditary Melanoma 2 | 12
Liver cancer 2 | 604
Lymphatic Diseases 2 | 14
Lymphoma 2 | 81
MELANOMA, CUTANEOUS MALIGNANT, 1 2 | 13
Melanocytic nevus 2 | 43
Nevus 2 | 19
Pick disease 2 | 1,894
Prominent back of the head 2 | 21
Prominent occiput 2 | 21
Schizophrenia 2 | 1,160
Short nose 2 | 132
Small nose 2 | 132
Vascular disease 2 | 319
Xerosis 2 | 75
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
hair abnormalities (non-specific) 2 | 30
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
spina bifida 2 | 1,074

Tissue

Endocrine System 14 | 18,159
Male tissues 14 | 17,142
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 8 | 4,145
Kinase 4 | 634
Non-IDG 2 | 12,091
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cyclin-dependent kinase 4 inhibitor B CDKN2B Tbio Enzyme -2.61258 428.8 451
Cyclin-dependent kinase 4 inhibitor C CDKN2C Tbio Enzyme -1.97718 112.7 386
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Cullin-1 CUL1 Tbio Non-IDG -2.37931 182.6 416
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.19296 1388.8 190
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509