Development Level

Tbio 19 | 11,445
Tchem 8 | 1,598
Tdark 6 | 6,588
Tclin 4 | 613

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Rheumatoid arthritis 17 | 1,191
lung carcinoma 14 | 2,843
Narcolepsy 12 | 72
lung cancer 12 | 4,740
sarcoidosis 12 | 370
Berylliosis 11 | 28
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
Multiple Sclerosis, Susceptibility to 10 | 15
Narcolepsy-cataplexy 10 | 21
Systemic lupus erythematosus 10 | 194
cutaneous lupus erythematosus 10 | 1,057
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Diffuse cutaneous systemic sclerosis 9 | 17
Rheumatoid Arthritis, Systemic Juvenile 9 | 16
Sarcoidosis 1 9 | 14
follicular lymphoma 9 | 20
limited scleroderma 9 | 19
invasive ductal carcinoma 8 | 2,951
Autosomal recessive predisposition 7 | 1,442
Cancer 7 | 2,499
Carcinoma 7 | 11,493
Hypersensitivity reaction type II disease 7 | 253
Juvenile rheumatoid arthritis 7 | 111
Multiple Sclerosis 7 | 540
breast carcinoma 7 | 1,638
ovarian cancer 7 | 8,520
primary Sjogren syndrome 7 | 735
Immunologic Deficiency Syndromes 6 | 113
glioblastoma 6 | 5,792
subependymal giant cell astrocytoma 6 | 2,287
Autoimmune Diseases 5 | 67
Celiac disease 5 | 116
Infantile onset 5 | 238
Recurrent respiratory infections 5 | 141
Schizophrenia 5 | 1,160
Type 1 diabetes mellitus 5 | 109
ulcerative colitis 5 | 1,819
Arthralgia 4 | 90
Arthritis, Rheumatoid 4 | 174
Asthma 4 | 385
Duchenne muscular dystrophy 4 | 601
Eczema 4 | 45
Failure to gain weight 4 | 365
Hepatitis B 4 | 108
Hypersensitivity 4 | 63
Pediatric failure to thrive 4 | 365
Recurrent infections 4 | 48
Severe combined immunodeficiency 4 | 51
Urticaria 4 | 67
active Crohn's disease 4 | 922
adult high grade glioma 4 | 3,801
juvenile dermatomyositis 4 | 1,187
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Addison's disease 3 | 31
Angioedema 3 | 38
Astrocytoma, Pilocytic 3 | 3,081
Autoimmune thyroiditis 3 | 27
Bipolar Disorder 3 | 666
C-reactive protein increased 3 | 15
Chronic Lymphocytic Leukemia 3 | 262
Collagen disease 3 | 27
Diabetes Mellitus, Insulin-Dependent 3 | 48
Diabetes Mellitus, Type 1 3 | 43
Diarrhea 3 | 253
ESR raised 3 | 20
Elevated C-reactive protein level 3 | 15
Erythema 3 | 58
Flushing 3 | 60
Graves' disease 3 | 24
Kidney cancer 3 | 2,613
Lymphopenia 3 | 67
Membranous glomerulonephritis 3 | 13
Oropharyngeal Neoplasms 3 | 4
Pre B-cell acute lymphoblastic leukemia 3 | 5
Proteinuria 3 | 144
Renal transplant rejection 3 | 13
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive 3 | 5
Systemic scleroderma 3 | 60
Vasculitis 3 | 80
Waldenstrons macroglobulinemia 3 | 765
Weight decreased 3 | 103
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
Chemical and Drug Induced Liver Injury 2 | 195
Chest Pain 2 | 38
Drug Eruptions 2 | 18
Fatigue 2 | 182
Fever 2 | 138
Liver disease 2 | 237
Liver diseases 2 | 87
Lymphoma 2 | 81
Nausea and vomiting 2 | 97
Somnolence 2 | 15
head and neck cancer and chronic obstructive pulmonary disease 2 | 239

Tissue

Blood and immune system 19 | 16,909
Liver and Pancreas 19 | 16,750
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Male tissues 18 | 17,142
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192
Nervous System 17 | 16,725

Target Family

Non-IDG 33 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

PathwayCommons: inoh Pathway

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