Development Level

Tbio 30 | 11,445
Tclin 5 | 613
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal eyelid morphology 1 | 7
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal placement of pupils 1 | 6
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased hemoglobin content 1 | 68
increased heart weight 1 | 62
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

ovarian cancer 31 | 8,520
Multiple myeloma 25 | 1,332
lung cancer 17 | 4,740
Carcinoma 16 | 11,493
psoriasis 16 | 6,694
osteosarcoma 14 | 7,950
HIV Infections 11 | 102
glioblastoma 11 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Waldenstrons macroglobulinemia 9 | 765
dermatomyositis 9 | 966
Breast cancer 8 | 3,578
Cancer 8 | 2,499
diabetes mellitus 7 | 1,728
subependymal giant cell astrocytoma 6 | 2,287
Mantle cell lymphoma 5 | 23
Pick disease 5 | 1,894
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
Astrocytoma, Pilocytic 4 | 3,081
Liver Cirrhosis, Experimental 4 | 769
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
astrocytoma 3 | 1,146
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Congestive heart failure 2 | 113
Osteoarthritis 2 | 184
Osteoporosis 2 | 363
Pulmonary Fibrosis 2 | 106
Ureteral obstruction 2 | 33
active Crohn's disease 2 | 922
astrocytic glioma 2 | 2,597
chronic kidney disease 2 | 90
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
Animal Mammary Neoplasms 1 | 136
Ankylosing spondylitis 1 | 140
Barrett's esophagus 1 | 182
Bone pain 1 | 42
Cardiomegaly 1 | 116
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Episcleritis 1 | 3
Erythema 1 | 58
Exanthema 1 | 43
Fatty Liver 1 | 70
Flushing 1 | 60
Full lower lip 1 | 64
Generalized osteopenia 1 | 99
Heart Diseases 1 | 43
Hereditary renal cell carcinoma 1 | 3
Hereditary spherocytosis type 5 1 | 12
Hyperhidrosis disorder 1 | 81
Hyperpigmentation 1 | 37
Hyperplasia of nose 1 | 23
Hypertensive Retinopathy 1 | 14
Hypertriglyceridemia result 1 | 37
Hypertrophy of nose 1 | 23
Increased sweating 1 | 81
Intermittent fever 1 | 15
Iron-Refractory Iron Deficiency Anemia 1 | 15
JMP syndrome 1 | 2
Joint stiffness 1 | 84
Large nose 1 | 23
Leber congenital amaurosis 1 | 69
Liver disease 1 | 237
Lymphadenopathy 1 | 62
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mild Mental Retardation 1 | 70
Myocardial Infarction 1 | 151
Osteopenia 1 | 99
Peripheral Neuropathy 1 | 134
Prominent lower lip 1 | 64
Stevens-Johnson syndrome 1 | 92
Sweating 1 | 81
Systemic scleroderma 1 | 60
Trachoma 1 | 5
Waterhouse-Friderichsen syndrome 1 | 11
maturity-onset diabetes of the young 1 | 32

Tissue

Blood and immune system 38 | 16,909
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678

Target Family

Enzyme 36 | 4,145
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 236 | 236
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Proteasome subunit alpha type-7 PSMA7 Tbio Enzyme -2.71627 496.7 288
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288
26S proteasome non-ATPase regulatory subunit 11 PSMD11 Tbio Enzyme -1.13234 13.3 211
Proteasome subunit alpha type-3 PSMA3 Tbio Enzyme -1.20981 15.8 181
Proteasome subunit alpha type-4 PSMA4 Tbio Enzyme -1.01237
Proteasome subunit alpha type-2 PSMA2 Tbio Enzyme -0.82346 5.78 245
26S proteasome non-ATPase regulatory subunit 6 PSMD6 Tbio Enzyme -1.35952 23.1 223
26S proteasome non-ATPase regulatory subunit 2 PSMD2 Tbio Enzyme -1.60281 36.3 389
Proteasome subunit beta type-8 PSMB8 Tclin Enzyme -2.43601 278.6 295