Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

decreased hemoglobin content 1 | 68
increased fasted circulating g... 1 | 76

Disease

Carcinoma 8 | 11,493
ovarian cancer 7 | 8,520
psoriasis 6 | 6,694
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
osteosarcoma 4 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Adenocarcinoma of lung 3 | 142
Autosomal recessive predisposition 3 | 1,442
Disease Models, Animal 3 | 155
Neuropathy 3 | 261
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Cancer 2 | 2,499
Coarse facial features 2 | 108
Cognitive delay 2 | 608
Congenital Epicanthus 2 | 177
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Dull intelligence 2 | 645
Epilepsy 2 | 792
Global developmental delay 2 | 608
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Long philtrum 2 | 137
Low intelligence 2 | 645
Low posterior hairline 2 | 52
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Myocardial Ischemia 2 | 169
Obesity 2 | 678
Peripheral Neuropathy 2 | 134
Poor school performance 2 | 645
Seizures 2 | 596
Splenomegaly 2 | 190
Synophrys 2 | 40
Thickened facial skin with coarse facial features 2 | 108
Type 2 diabetes mellitus 2 | 272
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
tuberculosis 2 | 2,010
Bilateral ptosis 1 | 9
Bone Diseases, Developmental 1 | 27
Cholelithiasis 1 | 33
Depletion of large myelinated fibers 1 | 7
Distal myopathy, Nonaka type 1 | 2
Downturned corners of mouth 1 | 48
EMG positive sharp waves 1 | 2
EMG: myopathic abnormalities 1 | 22
EMG: myotonic discharges 1 | 2
Fatty replacement of skeletal muscle 1 | 3
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Glycosuria 1 | 29
Hand deformities 1 | 32
Hard palate cancer 1 | 10
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Insulinoma 1 | 24
Irregular epiphyses 1 | 10
Irregular vertebral endplates 1 | 16
Limited shoulder movement 1 | 3
Limited wrist extension 1 | 2
Long hallux 1 | 5
Metaphyseal irregularity 1 | 23
NONAKA MYOPATHY 1 | 2
Normocytic anemia 1 | 6
Peripheral hypomyelination 1 | 7
Posterior scalloping of vertebral bodies 1 | 3
Prominent metopic ridge 1 | 15
Reflex, Ankle, Absent 1 | 8
Reticulocytosis 1 | 20
Rimmed vacuoles on biopsy 1 | 15
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Sialuria 1 | 9
Sleep Apnea Syndromes 1 | 13
Small epiphyses 1 | 9
Splayed metaphyses 1 | 19
Spondyloepimetaphyseal disorder 1 | 9
Tibialis muscle weakness 1 | 2
Variation in muscle fiber size 1 | 16
Weakness of hip flexors 1 | 2

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Kinase 5 | 634
Enzyme 4 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 9 | 9
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
N-acylneuraminate cytidylyltransferase CMAS Tbio Enzyme -3.22957 1646.9 83
Glucosamine 6-phosphate N-acetyltransferase GNPNAT1 Tbio Enzyme -1.45058 29.4 58
Sialic acid synthase NANS Tbio Enzyme -1.90302 79.7 128
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase GNE Tbio Enzyme -2.45989 288.1 185
Hexokinase-3 HK3 Tbio Kinase -1.72467 51.4 355
N-acetyl-D-glucosamine kinase NAGK Tbio Kinase -1.63894 41.9 210
Glucokinase GCK Tchem Kinase -2.90428 758.6 336
Hexokinase-1 HK1 Tchem Kinase -2.58967 375.7 571