Development Level

Tbio 9 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal eye size 1 | 7
abnormal gait 1 | 69
decreased mean corpuscular vol... 1 | 79
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 11 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 10 | 5,112
Cancer 9 | 2,499
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
glioblastoma 8 | 5,792
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
ependymoma 7 | 4,679
invasive ductal carcinoma 7 | 2,951
group 4 medulloblastoma 6 | 1,855
psoriasis 6 | 6,694
tuberculosis 6 | 2,010
Atopic dermatitis 5 | 952
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
lung carcinoma 5 | 2,843
Arthritis 4 | 290
Asthma 4 | 385
Inflammatory bowel disease 4 | 151
Multiple Sclerosis 4 | 540
Rheumatoid arthritis 4 | 1,191
astrocytic glioma 4 | 2,597
cutaneous lupus erythematosus 4 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Carcinoma, Hepatocellular 3 | 228
Hepatitis C 3 | 94
Liver carcinoma 3 | 240
Liver disease 3 | 237
Precancerous Conditions 3 | 80
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Adenocarcinoma 2 | 122
Animal Mammary Neoplasms 2 | 136
Arthritis, Experimental 2 | 39
Arthritis, Rheumatoid 2 | 174
Atherosclerosis 2 | 291
Breast Neoplasms 2 | 445
Candidiasis 2 | 55
Crohn's disease 2 | 321
Dermatitis 2 | 157
Dermatitis, Allergic Contact 2 | 67
Fever 2 | 138
Generalized osteopenia 2 | 99
Herpes zoster 2 | 68
Hypersensitivity reaction type II disease 2 | 253
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Liver Neoplasms, Experimental 2 | 59
Liver diseases 2 | 87
Lung disease 2 | 142
Lymphoma, T-Cell 2 | 13
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mastocytosis 2 | 27
Microphthalmia with limb anomalies 2 | 40
Multiple myeloma 2 | 1,332
Myocardial Ischemia 2 | 169
Neoplasm Metastasis 2 | 168
Obesity 2 | 678
Osteopenia 2 | 99
Pick disease 2 | 1,894
Polycythemia vera 2 | 27
Primary polycythemia 2 | 8
Recurrent respiratory infections 2 | 141
Reperfusion Injury 2 | 86
Short stature 2 | 531
Stuttering 2 | 17
Systemic lupus erythematosus 2 | 194
T-Cell Lymphoma 2 | 13
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
head and neck cancer 2 | 271
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 7 | 1,400

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 236 | 236
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
Suppressor of cytokine signaling 7 SOCS7 Tbio Non-IDG -1.64336 42.5 122
Signal transducer and activator of transcription 2 STAT2 Tbio Transcription Factor -2.43127 248.8 691
Signal transducer and activator of transcription 4 STAT4 Tbio Transcription Factor -2.51382 320.4 790
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.05851 1163.8 469
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Suppressor of cytokine signaling 6 SOCS6 Tbio Non-IDG -1.92284 79.5 154
Suppressor of cytokine signaling 3 SOCS3 Tbio Non-IDG -3.05657 1157.2 518
Suppressor of cytokine signaling 2 SOCS2 Tbio Non-IDG -2.90841 804.7 196