Development Level

Tchem 6 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
embryonic lethality prior to t... 1 | 278
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
Cancer 4 | 2,499
Cholestasis, Extrahepatic 4 | 25
adult high grade glioma 4 | 3,801
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Parkinson's disease 3 | 392
Reperfusion Injury 3 | 86
Vascular disease 3 | 319
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Brain Ischemia 2 | 110
Brain disease 2 | 96
Breast cancer 2 | 3,578
Cell Transformation, Neoplastic 2 | 97
Colonic Neoplasms 2 | 142
Disease Models, Animal 2 | 155
Eye disease 2 | 62
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hyperglycemia 2 | 137
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver disease 2 | 237
Lung disease 2 | 142
Neoplastic Cell Transformation 2 | 89
Obesity 2 | 678
Precancerous Conditions 2 | 80
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Stomach Neoplasms 2 | 300
Toxic encephalopathy 2 | 141
Trigeminal Neuralgia 2 | 24
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
ependymoma 2 | 4,679
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of the metaphyses 1 | 48
Abnormally-shaped vertebrae 1 | 31
Advanced bone age 1 | 35
Aggressive reaction 1 | 75
Amyotrophic lateral sclerosis 1 | 451
Autism Spectrum Disorders 1 | 75
Brain Injuries 1 | 65
Breast Neoplasms 1 | 445
Carcinoma, Hepatocellular 1 | 228
Conductive hearing loss 1 | 123
Congenital sensorineural hearing loss 1 | 12
Dental abnormalities 1 | 60
Disorder of eye 1 | 27
Downward slant of palpebral fissure 1 | 158
Encephalopathies 1 | 43
Eye Abnormalities 1 | 35
Fatty liver disease 1 | 103
Flexion contracture of proximal interphalangeal joint 1 | 75
Freckles 1 | 33
Hyperactive behavior 1 | 91
Hypersensitivity 1 | 63
Joint stiffness 1 | 84
Lennox-Gastaut syndrome 1 | 34
Liver Failure, Acute 1 | 29
Liver carcinoma 1 | 240
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Mental deterioration 1 | 32
Mitral valve insufficiency 1 | 49
Myoclonus 1 | 74
Neoplasm Metastasis 1 | 168
Neurodegenerative disease 1 | 414
Osteoporosis 1 | 363
Periodontal disease 1 | 40
Peripheral Neuropathy 1 | 134
Physical aggression 1 | 76
Sensorineural Hearing Loss (disorder) 1 | 284
Short thumb terminal phalanx 1 | 5
Tooth Abnormalities 1 | 69
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Kinase 5 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
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http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384
Dual specificity mitogen-activated protein kinase kinase 6 MAP2K6 Tchem Kinase -2.01763 74.4 636
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Transcription factor AP-1 JUN Tchem Transcription Factor -3.83935 6236.4 2664
Mitogen-activated protein kinase 8 MAPK8 Tchem Kinase -3.81256 5770.8 1150
Mitogen-activated protein kinase 9 MAPK9 Tchem Kinase -2.67320 359.2 611