Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating insulin ... 1 | 76
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased mean corpuscular vol... 1 | 92
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Cancer 14 | 2,499
ovarian cancer 12 | 8,520
Carcinoma 11 | 11,493
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
osteosarcoma 9 | 7,950
adult high grade glioma 8 | 3,801
ependymoma 7 | 4,679
medulloblastoma, large-cell 7 | 6,241
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
Hypercalcemia 5 | 59
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
medulloblastoma 5 | 720
primary pancreatic ductal adenocarcinoma 5 | 1,109
Abdominal pain, episodic 4 | 9
Acromegaly 4 | 51
Adrenal cortical adenoma 4 | 19
Angiofibroma 4 | 7
Astrocytoma, Pilocytic 4 | 3,081
Diarrhea 4 | 253
Esophagitis 4 | 35
Growth hormone excess 4 | 14
Hyperinsulinaemic hypoglycaemia 4 | 16
Hyperinsulinemia, fasting 4 | 7
Hyperparathyroidism 4 | 48
Increased serum parathyroid hormone 4 | 14
Insulinoma 4 | 24
Kidney cancer 4 | 2,613
Melanoma 4 | 711
Multiple Endocrine Neoplasia Type 1 4 | 29
Non-Functioning Pituitary Gland Neoplasm 4 | 6
Parathyroid Adenoma 4 | 19
Parathyroid hyperplasia 4 | 6
Peptic Ulcer 4 | 27
Pituitary growth hormone cell adenoma 4 | 8
Prolactinoma 4 | 11
Prostatic Neoplasms 4 | 495
Short stature 4 | 531
Stomach Neoplasms 4 | 300
Subcutaneous lipomas 4 | 9
Thyroid Gland Follicular Adenoma 4 | 9
Zollinger-Ellison syndrome 4 | 18
ductal carcinoma in situ 4 | 1,745
intermittent abdominal pain 4 | 9
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Adenoma 3 | 167
Carney complex 3 | 25
Concave bridge of nose 3 | 195
Congenital hypoplasia of penis 3 | 176
Cryptorchidism 3 | 296
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Gastrointestinal Stromal Tumors 3 | 48
Holoprosencephaly 3 | 56
Isolated somatotropin deficiency 3 | 30
Lung Neoplasms 3 | 232
Nevoid basal cell carcinoma syndrome 3 | 16
Parkinson's disease 3 | 392
Polydactyly 3 | 107
Small testicle 3 | 75
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Depressive disorder 2 | 409
Down syndrome 2 | 499
Epilepsy 2 | 792
Frontal bossing 2 | 157
Glaucoma 2 | 239
Highly variable severity 2 | 157
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Lymphoma 2 | 81
Pick disease 2 | 1,894
Prominent back of the head 2 | 21
Prominent occiput 2 | 21
Seizures 2 | 596
Short nose 2 | 132
Small nose 2 | 132
Urinary Bladder Neoplasms 2 | 114
Variable expressivity 2 | 157
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
spina bifida 2 | 1,074

Tissue

Endocrine System 16 | 18,159
Male tissues 16 | 17,142
Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Enzyme 8 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Non-IDG 2 | 12,091

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cyclin-dependent kinase 4 inhibitor B CDKN2B Tbio Enzyme -2.61258 428.8 451
Cyclin-dependent kinase 4 inhibitor C CDKN2C Tbio Enzyme -1.97718 112.7 386
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Cullin-1 CUL1 Tbio Non-IDG -2.37931 182.6 416
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.58228 355.0 196
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.19296 1388.8 190
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955