Development Level

Tbio 9 | 11,651
Tchem 6 | 1,388
Tclin 3 | 612

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased cardiac muscle contr... 1 | 8
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123

Disease

Carcinoma 17 | 11,493
lung cancer 13 | 4,740
ovarian cancer 12 | 8,520
psoriasis 11 | 6,694
invasive ductal carcinoma 10 | 2,951
ductal carcinoma in situ 8 | 1,745
medulloblastoma, large-cell 8 | 6,241
breast carcinoma 7 | 1,638
non-small cell lung cancer 7 | 2,890
osteosarcoma 7 | 7,950
pituitary cancer 7 | 1,972
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
Breast cancer 5 | 3,578
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Succinic semialdehyde dehydrogenase deficiency 5 | 16
acute myeloid leukemia 5 | 783
adult high grade glioma 5 | 3,801
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Schizophrenia 4 | 1,160
cystic fibrosis 4 | 1,696
interstitial lung disease 4 | 298
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alcohol abuse 3 | 50
Asthma 3 | 385
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Endometriosis 3 | 540
Hypertension 3 | 396
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
oligodendroglioma 3 | 2,850
Alcoholic Intoxication 2 | 34
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Carcinoma, Renal Cell 2 | 124
Colonic Neoplasms 2 | 142
Dementia 2 | 175
Diabetic Nephropathies 2 | 37
Diabetic Nephropathy 2 | 34
Dull intelligence 2 | 645
Epilepsy 2 | 792
Flushing 2 | 60
Hepatic encephalopathy 2 | 27
Hepatomegaly 2 | 285
Heroin dependence 2 | 30
Huntington Disease 2 | 13
Hypertensive disorder 2 | 57
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Mental deficiency 2 | 645
Mood Disorders 2 | 184
Myopia 2 | 176
Myositis 2 | 30
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Photodysphoria 2 | 121
Photophobia 2 | 121
Poor school performance 2 | 645
Renal Cell Carcinoma 2 | 214
Sensorineural Hearing Loss (disorder) 2 | 284
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
facioscapulohumeral dystrophy 2 | 288
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Respiratory system 17 | 16,393

Target Family

Enzyme 18 | 4,145

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.73034 52.5 194
Probable histidine--tRNA ligase, mitochondrial HARS2 Tbio Enzyme -2.45127 269.2 93
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.39309 2492.1 292
Membrane primary amine oxidase AOC3 Tchem Enzyme -2.79843 685.2 285
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.81062 648.3 725
Histidine decarboxylase HDC Tbio Enzyme -2.65393 472.2 175
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Histidine--tRNA ligase, cytoplasmic HARS Tchem Enzyme -1.85612 66.8 212
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Histamine N-methyltransferase HNMT Tchem Enzyme -2.88300 757.5 234