Development Level

Tchem 7 | 1,598
Tbio 6 | 11,445

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal vocalization 1 | 21
decreased bone mineral density 1 | 126
decreased circulating magnesiu... 1 | 13
decreased neutrophil cell numb... 1 | 42
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 9 | 11,493
osteosarcoma 8 | 7,950
ovarian cancer 7 | 8,520
psoriasis 6 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Epilepsy 3 | 792
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Myocardial Ischemia 3 | 169
Obesity 3 | 678
Poor school performance 3 | 645
Seizures 3 | 596
atypical teratoid / rhabdoid tumor 3 | 5,112
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
Achalasia 2 | 13
Adenocarcinoma of lung 2 | 142
Cancer 2 | 2,499
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Models, Animal 2 | 155
Feeding difficulties 2 | 127
Kidney cancer 2 | 2,613
Low Vision 2 | 174
Muscle Weakness 2 | 170
Neuropathy 2 | 261
Peripheral Neuropathy 2 | 134
Prenatal onset 2 | 139
Type 2 diabetes mellitus 2 | 272
Visual Impairment 2 | 174
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
type 2 diabetes 2 | 9
Alopecia areata 1 | 41
Arsenic Poisoning 1 | 62
Autonomic nervous system disorders 1 | 19
Axial hypotonia 1 | 46
Bilateral ptosis 1 | 9
Celiac disease 1 | 116
Charcot-Marie-Tooth disease 1 | 62
Cholecystitis 1 | 18
Congenital Heart Defects 1 | 58
Congenital heart disease 1 | 93
Decreased motor NCV 1 | 22
Deglutition Disorders 1 | 132
Dehydration 1 | 40
Dermatologic disorders 1 | 93
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Dysautonomia 1 | 20
Epilepsies, Myoclonic 1 | 32
Esophageal Achalasia 1 | 9
Esotropia 1 | 31
Generalized myoclonic seizures 1 | 30
Gestational diabetes 1 | 26
Granulomatous amebic encephalitis 1 | 8
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hypsarrhythmia 1 | 25
Increased bilirubin level (finding) 1 | 18
Insulin Resistance 1 | 72
Metabolic syndrome X 1 | 52
Myoclonic Epilepsies, Progressive 1 | 44
Palmoplantar keratosis 1 | 74
Pontine hypoplasia 1 | 7
Skin Diseases 1 | 71
Tonic - clonic seizures 1 | 44
maturity-onset diabetes of the young 1 | 32
non-inflammatory breast cancer 1 | 66
primary open angle glaucoma 1 | 16
triple-A syndrome 1 | 17

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Kinase 9 | 634
Enzyme 4 | 4,145

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 PFKFB4 Tchem Enzyme -1.28108 21.2 110
Mannose-1-phosphate guanyltransferase alpha GMPPA Tbio Enzyme -1.64224 42.1 100
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 PFKFB2 Tchem Kinase -1.65270 45.8 315
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 PFKFB1 Tbio Kinase -1.33284 17.6 214
Ketohexokinase KHK Tchem Kinase -1.99770 98.6 319
Hexokinase-3 HK3 Tbio Kinase -1.72467 51.4 355
Mannose-1-phosphate guanyltransferase beta GMPPB Tbio Enzyme -1.17283 16.0 118
Glucokinase GCK Tchem Kinase -2.90428 758.6 336
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PFKFB3 Tchem Kinase -2.28070 206.0 228