Development Level

Tchem 5 | 1,598
Tbio 3 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal testis morphology 1 | 43
absent testes 1 | 6
decreased eosinophil cell numb... 1 | 24
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37

Disease

Cancer 6 | 2,499
Carcinoma 6 | 11,493
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
Acquired scoliosis 5 | 281
Aortic Valve Insufficiency 5 | 40
Breast cancer 5 | 3,578
Byzanthine arch palate 5 | 194
Cleft Palate 5 | 271
Coronary artery disease 5 | 268
Curvature of spine 5 | 282
Hypertensive disease 5 | 292
juvenile dermatomyositis 5 | 1,187
ovarian cancer 5 | 8,520
Abnormality of the iris 4 | 14
Acquired flat foot 4 | 72
Aortic aneurysm, familial thoracic 3 4 | 13
Arachnodactyly 4 | 49
Ascending aortic dissection 4 | 13
Astrocytoma, Pilocytic 4 | 3,081
Cardiomegaly 4 | 116
Chest Pain 4 | 38
Cutis marmorata 4 | 32
Cystic medial necrosis of aorta 4 | 13
Descending aortic dissection 4 | 13
Dyspnea on exertion 4 | 24
Dyspnea, Paroxysmal 4 | 13
Familial thoracic aortic aneurysm and aortic dissection 4 | 13
Flatfoot 4 | 73
Impaired left ventricular function 4 | 16
Increase in blood pressure 4 | 119
Left-Sided Heart Failure 4 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 4 | 13
Loeys-Dietz syndrome 4 | 23
Orbital separation excessive 4 | 244
Tall stature 4 | 34
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
medulloblastoma, large-cell 4 | 6,241
Aortic aneurysm 3 | 38
Arterial tortuosity 3 | 5
Blue sclera 3 | 32
Cleft uvula 3 | 27
Craniosynostosis 3 | 74
Dissection of aorta 3 | 9
Exophthalmos 3 | 112
Eye Abnormalities 3 | 35
Flexion contracture of proximal interphalangeal joint 3 | 75
Hernia, Inguinal 3 | 89
Hypoplastic mandible condyle 3 | 275
Liver Cirrhosis, Experimental 3 | 769
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Prominent eyes 3 | 96
Prominent globes 3 | 96
Prostatic Neoplasms 3 | 495
Protruding eyes 3 | 96
Pulmonary Fibrosis 3 | 106
Retrognathia 3 | 54
Thoracic aortic aneurysm 3 | 15
Ureteral obstruction 3 | 33
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abortion, Spontaneous 2 | 109
Attention deficit hyperactivity disorder 2 | 278
Atypical scarring of skin 2 | 62
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Decreased antibody level in blood 2 | 35
Dental caries 2 | 164
Depressive disorder 2 | 409
Diabetic Nephropathies 2 | 37
Esophageal Neoplasms 2 | 69
Gaucher disease type 1 2 | 180
Hypogammaglobulinemia 2 | 35
Hypotrophic malar bone 2 | 129
Immunologic Deficiency Syndromes 2 | 113
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Malabsorption 2 | 82
Malar flattening 2 | 129
Neoplasm Metastasis 2 | 168
Polycystic ovary syndrome 2 | 360
Schizophrenia 2 | 1,160
Skull malformation 2 | 38
Spontaneous abortion 2 | 113
Squamous cell carcinoma 2 | 129
active ulcerative colitis 2 | 764
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non-small cell lung cancer 2 | 2,890

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Kinase 4 | 634
Non-IDG 3 | 12,091
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
E3 ubiquitin-protein ligase XIAP XIAP Tchem Enzyme -3.13488 1375.8 504
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TAB1 Tbio Kinase -1.94861 84.9 478