Development Level

Tchem 6 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased vertical activity 1 | 208
increased circulating glucose ... 1 | 24
male infertility 1 | 123
prenatal lethality 1 | 28
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 8 | 11,493
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
astrocytic glioma 6 | 2,597
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
Abnormal dermatoglyphic pattern 5 | 24
Blepharoptosis 5 | 231
Byzanthine arch palate 5 | 194
Cardiac Arrhythmia 5 | 103
Cardiac conduction abnormalities 5 | 78
Conduction disorder of the heart 5 | 79
Congenital pectus carinatum 5 | 52
Cryptorchidism 5 | 296
Curly hair (finding) 5 | 14
Delayed bone age 5 | 136
Downward slant of palpebral fissure 5 | 158
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Excess nuchal skin 5 | 30
Full lower lip 5 | 64
Hypoplastic mandible condyle 5 | 275
Joint hyperflexibility 5 | 78
Kidney cancer 5 | 2,613
Low set ears 5 | 181
Mandibular hypoplasia 5 | 275
Melanocytic nevus 5 | 43
Micrognathism 5 | 275
Muscle hypotonia 5 | 571
Neck webbing 5 | 35
Noncancerous mole 5 | 28
Noonan syndrome 5 | 34
Orbital separation excessive 5 | 244
Prominent lower lip 5 | 64
Short stature 5 | 531
Strabismus 5 | 270
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
Abnormality of pulmonary valve 4 | 23
Abnormality of vision 4 | 40
Acquired scoliosis 4 | 281
Bleeding tendency 4 | 37
Blood Coagulation Disorders 4 | 42
Breast Neoplasms 4 | 445
Chubby cheeks 4 | 50
Coagulation abnormalities 4 | 27
Coarse hair 4 | 31
Concave bridge of nose 4 | 195
Congenital Epicanthus 4 | 177
Curvature of spine 4 | 282
Decreased projection of midface 4 | 105
Decreased width of the skull 4 | 28
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Dull intelligence 4 | 645
Dysarthria 4 | 192
Electroencephalogram abnormal 4 | 101
Epilepsy 4 | 792
Exophthalmos 4 | 112
Feeding difficulties in infancy 4 | 175
Frontal bossing 4 | 157
Generalized osteopenia 4 | 99
Hemangioma, Cavernous 4 | 20
Hemorrhagic Disorders 4 | 30
Hepatomegaly 4 | 285
High forehead 4 | 102
Hyperplasia of cheeks 4 | 50
Hypertrophy of cheeks 4 | 50
Hypogonadism, Isolated Hypogonadotropic 4 | 71
Hypogonadotropic hypogonadism 4 | 89
Hypotrophic midface 4 | 105
Ichthyoses 4 | 41
Kyphoscoliosis deformity of spine 4 | 60
Liver neoplasms 4 | 130
Low posterior hairline 4 | 52
Lung Neoplasms 4 | 232
Lymphangioma, Cystic 4 | 21
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Midface retrusion 4 | 105
Muscle Weakness 4 | 170
Osteopenia 4 | 99
Pectus excavatum 4 | 100
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Puffy cheeks 4 | 50
Pulmonary Stenosis 4 | 45
Pulmonary artery stenosis 4 | 22
Rough hair texture 4 | 31
Seizures 4 | 596
Small midface 4 | 105
Tall forehead 4 | 102
Thyroid cancer 4 | 36
Triangular face 4 | 58
psoriasis 4 | 6,694

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Kinase 4 | 634
Enzyme 3 | 4,145
Non-IDG 1 | 12,091

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
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http://pathwaycommons.org/pc2/... 51 | 51
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http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
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http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
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http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
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http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
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http://pathwaycommons.org/pc2/... 20 | 20
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http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
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http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
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http://pathwaycommons.org/pc2/... 19 | 19
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http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
RAS guanyl-releasing protein 1 RASGRP1 Tchem Non-IDG -1.99263 105.6 99
Serine/threonine-protein kinase A-Raf ARAF Tchem Kinase -2.46615 277.6 465
Serine/threonine-protein kinase B-raf BRAF Tclin Kinase -2.33582 220.9 1431
Protein kinase C theta type PRKCQ Tchem Kinase -1.08459 10.8 592
RAF proto-oncogene serine/threonine-protein kinase RAF1 Tclin Kinase -3.11577 1210.8 2254