Development Level

Tbio 7 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal lens morphology 1 | 81
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased eosinophil cell numb... 1 | 11
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

psoriasis 10 | 6,694
Carcinoma 9 | 11,493
lung cancer 9 | 4,740
Cancer 8 | 2,499
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
Arthritis 6 | 290
Astrocytoma, Pilocytic 6 | 3,081
Rheumatoid arthritis 6 | 1,191
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
tuberculosis 6 | 2,010
Hypersensitivity reaction type II disease 5 | 253
Inflammatory bowel disease 5 | 151
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
dermatomyositis 5 | 966
oligodendroglioma 5 | 2,850
Asthma 4 | 385
Brain Injuries 4 | 65
Cholestasis, Extrahepatic 4 | 25
Coronary artery disease 4 | 268
Cryopyrin associated periodic syndrome 4 | 5
Inflammation 4 | 120
Meningitis 4 | 67
Pneumonia 4 | 174
Reperfusion Injury 4 | 86
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Alcoholic Intoxication, Chronic 3 | 289
Allergic hypersensitivity disease 3 | 126
Arthritis, Rheumatoid 3 | 174
Burns, Chemical 3 | 6
Chorioamnionitis 3 | 14
Dermatitis 3 | 157
Dermatologic disorders 3 | 93
Diarrhea 3 | 253
Endometriosis 3 | 540
Fever 3 | 138
Hypertension 3 | 396
Hypertensive disease 3 | 292
Influenza 3 | 142
Kidney disease 3 | 430
Malaria 3 | 160
Melioidosis 3 | 17
Multiple Sclerosis 3 | 540
Neoplasm Invasiveness 3 | 161
Osteoporosis 3 | 363
Peritonitis 3 | 43
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Salmonellosis 3 | 42
Schizophrenia 3 | 1,160
Skin Diseases 3 | 71
acute quadriplegic myopathy 3 | 1,158
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
periodontitis 3 | 293
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Arsenic Poisoning 2 | 62
Atherosclerosis 2 | 291
Brain Ischemia 2 | 110
Cardiomyopathies 2 | 110
Cerebrovascular disease 2 | 238
Chemical and Drug Induced Liver Injury 2 | 195
Chronic progressive external ophthalmoplegia 2 | 26
Colitis 2 | 54
Disease Models, Animal 2 | 155
Disease Progression 2 | 136
Eye disease 2 | 62
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hypersensitivity 2 | 63
Keratitis 2 | 62
Leishmaniasis 2 | 47
Leukopenia 2 | 72
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Myocardial Ischemia 2 | 169
Parasitic helminthiasis infectious disease 2 | 15
Type 2 diabetes mellitus 2 | 272
Vasculitis 2 | 80
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 10 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 236 | 236
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.28820 202.2 610
Ubiquitin-conjugating enzyme E2 N UBE2N Tbio Non-IDG -2.08846 107.8 268
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.90517 75.2 151
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.68139 387.6 620
Interleukin-1 alpha IL1A Tchem Non-IDG -3.56722 3688.9 1000