Development Level

Tchem 11 | 1,598
Tbio 10 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

atypical teratoid / rhabdoid tumor 16 | 5,112
Cancer 15 | 2,499
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
ovarian cancer 14 | 8,520
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
psoriasis 12 | 6,694
Carcinoma 11 | 11,493
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
Astrocytoma, Pilocytic 9 | 3,081
Vascular disease 8 | 319
oligodendroglioma 8 | 2,850
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Breast cancer 6 | 3,578
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Bipolar Disorder 5 | 666
Rheumatoid arthritis 5 | 1,191
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Autoimmune lymphoproliferative syndrome 4 | 11
Cardiomyopathies 4 | 110
Diabetes Mellitus, Experimental 4 | 108
Kidney cancer 4 | 2,613
Lung Neoplasms 4 | 232
Neurodegenerative disease 4 | 414
Parkinson's disease 4 | 392
Toxic encephalopathy 4 | 141
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
malignant mesothelioma 4 | 3,232
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Arthritis 3 | 290
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Disease Models, Animal 3 | 155
Epilepsy 3 | 792
Esophageal Neoplasms 3 | 69
Eye disease 3 | 62
Hypersensitivity reaction type II disease 3 | 253
Ischemia 3 | 28
Liver Failure, Acute 3 | 29
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Myocardial Reperfusion Injury 3 | 37
Neoplasm Metastasis 3 | 168
Precancerous Conditions 3 | 80
Reperfusion Injury 3 | 86
Splenomegaly 3 | 190
Stomach Neoplasms 3 | 300
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
Brain Ischemia 2 | 110
Cardiomyopathy, Dilated 2 | 83
Cerebral atrophy 2 | 178
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hyperalgesia 2 | 83
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Lung disease 2 | 142
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Urticaria 2 | 67
Vasculitis 2 | 80
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 14 | 12,091
Kinase 6 | 634
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384
14-3-3 protein zeta/delta YWHAZ Tbio Non-IDG -2.59435 390.4 689
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.66223 525.4 1185
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060