Development Level

Tbio 54 | 11,445
Tclin 30 | 613
Tchem 10 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

increased neutrophil cell numb... 5 | 46
enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
improved glucose tolerance 3 | 79
increased monocyte cell number 3 | 63
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased heart weight 2 | 27
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
female infertility 2 | 60
hypoactivity 2 | 132
impaired righting response 2 | 26
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased circulating total pr... 2 | 28
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
male infertility 2 | 123
abnormal brain morphology 1 | 13
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
corneal opacity 1 | 32
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged liver 1 | 2
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Cancer 60 | 2,499
Carcinoma 58 | 11,493
psoriasis 54 | 6,694
lung cancer 46 | 4,740
osteosarcoma 46 | 7,950
ovarian cancer 40 | 8,520
malignant mesothelioma 39 | 3,232
lung carcinoma 35 | 2,843
Asthma 34 | 385
glioblastoma 34 | 5,792
Rheumatoid arthritis 33 | 1,191
tuberculosis 33 | 2,010
ulcerative colitis 31 | 1,819
medulloblastoma, large-cell 29 | 6,241
interstitial cystitis 28 | 2,312
Hypersensitivity reaction type II disease 27 | 253
Multiple Sclerosis 27 | 540
Astrocytoma, Pilocytic 26 | 3,081
Inflammatory bowel disease 26 | 151
Anemia 24 | 365
Arthritis 24 | 290
Pneumonia 23 | 174
pancreatic cancer 23 | 2,398
Schizophrenia 22 | 1,160
lung adenocarcinoma 22 | 2,716
cutaneous lupus erythematosus 21 | 1,057
adult high grade glioma 20 | 3,801
non-small cell lung cancer 20 | 2,890
Breast cancer 19 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
diabetes mellitus 18 | 1,728
Hypereosinophilic syndrome 17 | 71
Influenza 17 | 142
atypical teratoid / rhabdoid tumor 17 | 5,112
invasive ductal carcinoma 17 | 2,951
periodontitis 17 | 293
pituitary cancer 17 | 1,972
Allergic hypersensitivity disease 16 | 126
Arthritis, Rheumatoid 16 | 174
Dermatitis 16 | 157
Fever 16 | 138
Hepatitis B 16 | 108
Hypersensitivity 16 | 63
Thrombocytopenia 16 | 197
cystic fibrosis 16 | 1,696
ependymoma 16 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Atopic dermatitis 15 | 952
Autosomal recessive predisposition 15 | 1,442
Allergic rhinitis 14 | 94
Brain Injuries 14 | 65
Diarrhea 14 | 253
Hepatitis C 14 | 94
Kidney disease 14 | 430
Leukopenia 14 | 72
Liver Cirrhosis, Experimental 14 | 769
Lung disease 14 | 142
Melanoma 14 | 711
Vasculitis 14 | 80
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
sarcoidosis 14 | 370
Abortion, Spontaneous 13 | 109
Breast Neoplasms 13 | 445
Crohn's disease 13 | 321
Endometriosis 13 | 540
Inflammation 13 | 120
Mammary Neoplasms 13 | 425
Spontaneous abortion 13 | 113
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
subependymal giant cell astrocytoma 13 | 2,287
Candidiasis 12 | 55
Chemical and Drug Induced Liver Injury 12 | 195
Leishmaniasis 12 | 47
Liver disease 12 | 237
Multiple myeloma 12 | 1,332
group 3 medulloblastoma 12 | 4,104
primary Sjogren syndrome 12 | 735
Acquired immunodeficiency syndrome 11 | 197
Ankylosing spondylitis 11 | 140
Arthralgia 11 | 90
Atherosclerosis 11 | 291
Brain Ischemia 11 | 110
Colitis, Ulcerative 11 | 59
Depressive disorder 11 | 409
Heart disease 11 | 306
Human immunodeficiency virus infectious disease 11 | 138
Kidney cancer 11 | 2,613
Malaria 11 | 160
Myocardial Infarction 11 | 151
Prostatic Neoplasms 11 | 495
Pulmonary Fibrosis 11 | 106
colon cancer 11 | 1,478
non-small cell lung carcinoma 11 | 317
Major Depressive Disorder 10 | 301
Mental Depression 10 | 333
Myocardial Ischemia 10 | 169
Unipolar Depression 10 | 250
ductal carcinoma in situ 10 | 1,745
mucosa-associated lymphoid tissue lymphoma 10 | 484
oligodendroglioma 10 | 2,850

Tissue

Blood and immune system 85 | 16,909
Male tissues 82 | 17,142
Endocrine System 81 | 18,159
Skin and soft tissues 81 | 17,230
Urinary Tract 81 | 16,678
Digestive Tract 80 | 17,369
Liver and Pancreas 79 | 16,750
Respiratory system 79 | 16,393
Female tissues 77 | 17,400
Nervous System 76 | 16,725
Cardiovascular System 69 | 15,192

Target Family

Non-IDG 83 | 12,091
Transcription Factor 7 | 1,400
Kinase 4 | 634
GPCR 2 | 408

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615