Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal body wall morphology 1 | 9
abnormal embryo size 1 | 220
anophthalmia 1 | 33
increased body length 1 | 32
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 2 | 11,493
beta-ketothiolase deficiency 2 | 13
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Acetyl-Coa Acetyltransferase-2 Deficiency 1 | 1
Alpha-Methylacetoacetic Aciduria 1 | 1
Autosomal recessive predisposition 1 | 1,442
Beta ketothiolase deficiency 1 | 1
Chorea 1 | 29
Choreatic disease 1 | 52
Cognitive delay 1 | 608
Cytosolic acetoacetyl-CoA thiolase deficiency 1 | 1
Deficiency of acetyl-CoA acetyltransferase 1 | 1
Dehydration 1 | 40
Dull intelligence 1 | 645
Gaucher's disease 1 | 26
Global developmental delay 1 | 608
Hydrolethalus syndrome 1 | 128
Increased serum lactate 1 | 60
Increased serum pyruvate 1 | 9
Intellectual disability 1 | 1,016
Isolated cases 1 | 72
Ketoacidosis, episodic 1 | 4
Kidney Failure, Chronic 1 | 46
Liver Cirrhosis, Experimental 1 | 769
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Multiple myeloma 1 | 1,332
Muscle hypotonia 1 | 571
Poor school performance 1 | 645
Seizures 1 | 596
Vomiting 1 | 116
Waldenstrons macroglobulinemia 1 | 765
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
colon cancer 1 | 1,478
ductal carcinoma in situ 1 | 1,745
fibroadenoma 1 | 559
gastric carcinoma 1 | 807
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
malignant mesothelioma 1 | 3,232
nephrosclerosis 1 | 333
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 2 | 2
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetyl-CoA acetyltransferase, cytosolic ACAT2 Tbio Enzyme -1.75917 52.6 283
Acetyl-CoA acetyltransferase, mitochondrial ACAT1 Tchem Enzyme -1.85518 70.4 397