Development Level

Tbio 4 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Cancer 7 | 2,499
Carcinoma 7 | 11,493
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Breast cancer 5 | 3,578
Liver Cirrhosis, Experimental 5 | 769
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
ovarian cancer 5 | 8,520
Myocardial Ischemia 4 | 169
Obesity 4 | 678
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
tuberculosis 4 | 2,010
Anemia 3 | 365
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Delayed bone age 3 | 136
Dwarfism 3 | 37
Mastocytosis 3 | 27
Polycythemia vera 3 | 27
Primary polycythemia 3 | 8
Short stature 3 | 531
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Abnormality of metabolism/homeostasis 2 | 134
Acromegaly 2 | 51
Adenocarcinoma 2 | 122
Arthritis 2 | 290
Arthropathy 2 | 43
Autosomal recessive predisposition 2 | 1,442
Bleeding tendency 2 | 37
Brachydactyly 2 | 156
Congenital anomaly of face 2 | 56
Congenital hypoplasia of penis 2 | 176
Delayed Puberty 2 | 97
Delayed menarche 2 | 3
Dermatitis, Allergic Contact 2 | 67
Hepatitis C 2 | 94
Hepatomegaly 2 | 285
High forehead 2 | 102
Hypoglycemia 2 | 152
Hypopituitarism 2 | 40
Hypoplastic mandible condyle 2 | 275
Hypothyroidism 2 | 122
Immune system cancer 2 | 140
Isolated somatotropin deficiency 2 | 30
Kidney cancer 2 | 2,613
Laron syndrome 2 | 6
Leukemia 2 | 104
Leukemia, Myeloid, Acute 2 | 105
Liver Neoplasms, Experimental 2 | 59
Liver disease 2 | 237
Liver diseases 2 | 87
Lymphoid leukemia 2 | 160
Mammary Neoplasms, Experimental 2 | 154
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Noonan syndrome 2 | 34
Pituitary dwarfism 2 | 6
Polycythemia 2 | 25
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Short Stature, Idiopathic, Autosomal 2 | 4
Short stature due to partial GHR deficiency 2 | 3
Somatic mutation 2 | 61
Systemic lupus erythematosus 2 | 194
Tall forehead 2 | 102
Turner syndrome 2 | 28
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
joint abnormality 2 | 5
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Factor XII deficiency 1 | 13
Limited elbow movement 1 | 6
Scapular weakness 1 | 23
Small face 1 | 10
Winged scapula 1 | 23

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Respiratory system 9 | 16,393
Cardiovascular System 8 | 15,192
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.05851 1163.8 469
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Somatotropin GH1 Tbio Non-IDG -3.03406 1736.7 722
Suppressor of cytokine signaling 3 SOCS3 Tbio Non-IDG -3.05657 1157.2 518
Suppressor of cytokine signaling 2 SOCS2 Tbio Non-IDG -2.90841 804.7 196
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Growth hormone receptor GHR Tclin Non-IDG -3.11970 1322.6 236
Tyrosine-protein kinase JAK2 JAK2 Tclin Kinase -3.54037 3339.7 801
Signal transducer and activator of transcription 5A STAT5A Tchem Transcription Factor -3.02609 960.2 1216