Development Level

Tbio 9 | 11,445

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
increased circulating triglyce... 1 | 42
increased neutrophil cell numb... 1 | 46
mydriasis 1 | 6

Disease

psoriasis 9 | 6,694
glioblastoma 8 | 5,792
ovarian cancer 7 | 8,520
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Cancer 5 | 2,499
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Duchenne muscular dystrophy 3 | 601
Hypersensitivity reaction type II disease 3 | 253
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Arthritis 2 | 290
Atrial Septal Defects 2 | 85
Broad flat nasal bridge 2 | 236
Cleft Palate 2 | 271
Congenital clubfoot 2 | 109
Craniofacial Abnormalities 2 | 151
Cryptorchidism 2 | 296
Curvature of spine 2 | 282
Down syndrome 2 | 499
Gaucher disease type 1 2 | 180
Hernia, Inguinal 2 | 89
Kidney disease 2 | 430
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Low-set, posteriorly rotated ears 2 | 110
Myopathy 2 | 185
Nasal bridge wide 2 | 236
Short neck 2 | 140
Simpson-Golabi-Behmel syndrome 2 | 19
Umbilical hernia 2 | 93
Uranostaphyloschisis 2 | 167
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
fascioscapulohumeral muscular dystrophy 2 | 100
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
limb girdle muscular dystrophy 2A 2 | 213
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
non primary Sjogren syndrome sicca 2 | 891
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
Abnormal helices 1 | 11
Acquired flat foot 1 | 72
Adenomatous Polyposis Coli 1 | 16
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Congenital Myasthenic Syndromes, Presynaptic 1 | 8
Congenital pectus carinatum 1 | 52
Endometritis 1 | 21
Erythema multiforme 1 | 17
Everted lower lip vermilion 1 | 54
Exanthem 1 | 37
Fetal overgrowth 1 | 16
Flatfoot 1 | 73
Gastrointestinal system disease 1 | 54
Generalized overgrowth 1 | 16
Hip joint varus deformity - observation 1 | 24
Hyperkyphosis 1 | 111
Kyphosis deformity of spine 1 | 114
Macroglobulinemia 1 | 18
Malignant hyperpyrexia due to anesthesia 1 | 10
Malocclusion 1 | 57
Micronychia (disorder) 1 | 24
Myasthenia gravis 1 | 23
Overfolded helix 1 | 24
Overgrowth 1 | 16
Platyspondyly 1 | 56
Protruding lower lip 1 | 54
Schwartz-Jampel syndrome 1 1 | 3
Short distal phalanges 1 | 50
Short hands 1 | 50

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
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http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
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http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Glypican-1 GPC1 Tbio Non-IDG -2.38207 232.3 202
Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 Tbio Enzyme -2.99264 1021.1 225
Syndecan-1 SDC1 Tbio Non-IDG -3.25832 1806.2 994
CD44 antigen CD44 Tbio Non-IDG -3.85987 6832.7 3401
Glypican-4 GPC4 Tbio Non-IDG -1.59066 43.7 257
Agrin AGRN Tbio Non-IDG -2.73844 569.8 122
Syndecan-2 SDC2 Tbio Non-IDG -2.09765 138.1 184