Development Level

Tclin 5 | 613
Tchem 1 | 1,598

IMPC Phenotype

decreased circulating glucose ... 1 | 126
decreased total body fat amoun... 1 | 207
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Cancer 6 | 2,499
Rheumatoid arthritis 6 | 1,191
lung cancer 6 | 4,740
Carcinoma 5 | 11,493
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
ulcerative colitis 5 | 1,819
Anemia 4 | 365
Multiple myeloma 4 | 1,332
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
pituitary cancer 4 | 1,972
Angiofollicular lymph node hyperplasia 3 | 3
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Brain Ischemia 3 | 110
Depressive disorder 3 | 409
Fever 3 | 138
Immune system cancer 3 | 140
Infarction, Middle Cerebral Artery 3 | 33
Inflammation 3 | 120
Juvenile rheumatoid arthritis 3 | 111
Liver Neoplasms, Experimental 3 | 59
Lymphoid leukemia 3 | 160
Myocardial Ischemia 3 | 169
Obesity 3 | 678
Ovarian Neoplasms 3 | 102
Pneumonia 3 | 174
Prostatic Neoplasms 3 | 495
Reperfusion Injury 3 | 86
Stomach Neoplasms 3 | 300
Thrombocytopenia 3 | 197
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
ovarian neoplasm 3 | 99
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Abortion, Spontaneous 2 | 109
Animal Mammary Neoplasms 2 | 136
Arthralgia 2 | 90
Autoimmune Diseases 2 | 67
Breast Neoplasms 2 | 445
Candidiasis 2 | 55
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Renal Cell 2 | 124
Cardiomyopathies 2 | 110
Chronic obstructive pulmonary disease 2 | 184
Dermatitis 2 | 157
Headache 2 | 37
Heart disease 2 | 306
Hypereosinophilic syndrome 2 | 71
Hypersensitivity 2 | 63
Hypersensitivity reaction type II disease 2 | 253
Inflammatory bowel disease 2 | 151
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver Cirrhosis 2 | 181
Liver disease 2 | 237
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Myelofibrosis 2 | 14
Myocardial Infarction 2 | 151
Neoplasm Metastasis 2 | 168
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Polycythemia vera 2 | 27
Pruritus 2 | 58
Renal Cell Carcinoma 2 | 214
Schizophrenia 2 | 1,160
Spontaneous abortion 2 | 113
Squamous cell carcinoma 2 | 129
Thrombocytosis 2 | 38
Uterine Cervical Neoplasms 2 | 26
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
non-small cell lung carcinoma 2 | 317
primary Sjogren syndrome 2 | 735
tuberculosis 2 | 2,010

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 3 | 12,091
Kinase 2 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Interleukin-6 receptor subunit alpha IL6R Tclin Non-IDG -2.52639 271.6 613
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Tyrosine-protein kinase JAK1 JAK1 Tclin Kinase -2.80024 518.7 425
Tyrosine-protein kinase JAK2 JAK2 Tclin Kinase -3.54037 3339.7 801