Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
abnormal vitreous body morphol... 1 | 10
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Porphyria 7 | 10
osteosarcoma 7 | 7,950
Hereditary coproporphyria 6 | 8
Variegate Porphyria 6 | 10
Acute intermittent porphyria 5 | 15
Photosensitivity of skin 5 | 51
Porphyria cutanea tarda 5 | 12
Abdominal Pain 4 | 98
Anemia, Hemolytic 4 | 55
Carcinoma 4 | 11,493
Constipation 4 | 181
Dyschezia 4 | 135
Erythropoietic protoporphyria 4 | 15
Vomiting 4 | 116
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
ovarian cancer 4 | 8,520
Abnormal blistering of the skin 3 | 54
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Blister of skin 3 | 54
Cutaneous porphyria 3 | 6
Diarrhea 3 | 253
Elevated heart rate 3 | 25
Hypertensive disease 3 | 292
Peripheral Neuropathy 3 | 134
Respiratory Paralysis 3 | 7
Skin bulla 3 | 54
Tachycardia 3 | 43
Thin skin 3 | 47
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Abnormality of the heme biosynthetic pathway 2 | 3
Acute episodes of neuropathic symptoms 2 | 2
Alopecia 2 | 115
Anxiety 2 | 136
Anxiety disease 2 | 113
Cholelithiasis 2 | 33
Depressive disorder 2 | 409
Elevated urinary delta-aminolevulinic acid 2 | 3
Hepatoerythropoietic porphyria 2 | 5
Hypertrichosis 2 | 46
Increase in blood pressure 2 | 119
Increased hepatocellular carcinoma risk 2 | 27
Increased incidence of hepatocellular carcinoma 2 | 27
Liver Cirrhosis 2 | 181
Liver carcinoma 2 | 240
Myalgia 2 | 54
Nausea and vomiting 2 | 97
Neuropathy 2 | 261
Paresthesia 2 | 32
Psychotic Disorders 2 | 151
Scleroderma 2 | 7
Scleroderma-like secondary cutaneous sclerosis 2 | 7
Seizures 2 | 596
Sleeplessness 2 | 16
Splenomegaly 2 | 190
Urine color abnormal 2 | 6
cutaneous lupus erythematosus 2 | 1,057
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Anorexia 1 | 43
Carcinoma, Renal Cell 1 | 124
Cicatrization 1 | 3
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Confusion 1 | 21
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Corneal Scar 1 | 7
Edema 1 | 81
Erythema 1 | 58
Fibrosis 1 | 44
Flushing 1 | 60
Fragile skin 1 | 18
Generalized osteopenia 1 | 99
Head and Neck Neoplasms 1 | 26
Hyperpigmentation 1 | 37
Hyperpigmented macules 1 | 42
Hypertriglyceridemia result 1 | 37
Hypospadias 1 | 53
Inverted follicular keratosis 1 | 3
Irritation - emotion 1 | 68
Lytic lesion 1 | 32
Meningioma 1 | 41
Nausea 1 | 20
Osteopenia 1 | 99
Paralytic ileus 1 | 5
Pathological fracture 1 | 20
Renal Cell Carcinoma 1 | 214
Respiratory Distress Syndrome, Adult 1 | 40
Silver-Russell syndrome 1 | 39
Tyrosinemia 1 | 10
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 7 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
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http://pathwaycommons.org/pc2/... 51 | 51
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http://pathwaycommons.org/pc2/... 40 | 40
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http://pathwaycommons.org/pc2/... 35 | 35
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http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial CPOX Tbio Enzyme -2.05504 112.4 87
Protoporphyrinogen oxidase PPOX Tchem Enzyme -2.47389 296.8 173
Porphobilinogen deaminase HMBS Tbio Enzyme -2.78202 588.5 255
Delta-aminolevulinic acid dehydratase ALAD Tbio Enzyme -3.02024 1068.6 166
Uroporphyrinogen-III synthase UROS Tbio Enzyme -2.48982 310.9 67
Ferrochelatase, mitochondrial FECH Tbio Enzyme -2.73759 528.2 136
Uroporphyrinogen decarboxylase UROD Tbio Enzyme -2.94694 872.4 188