Development Level

Tbio 7 | 11,445
Tchem 6 | 1,598

Disease

ovarian cancer 12 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
Cancer 7 | 2,499
Short stature 6 | 531
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Astrocytoma, Pilocytic 4 | 3,081
Bilateral fifth finger clinodactyly 4 | 110
Breast Neoplasms 4 | 445
Broad hallux 4 | 29
Craniofacial Abnormalities 4 | 151
Curvature of little finger 4 | 110
Decreased projection of maxilla 4 | 66
Deficiency of upper jaw bones 4 | 66
Dull intelligence 4 | 645
Enophthalmos 4 | 75
Failure to gain weight 4 | 365
Hypoplasia of the maxilla 4 | 66
Hypotrophic maxilla 4 | 66
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Maxillary retrognathia 4 | 66
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Microstomia 4 | 78
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
Retrusion of upper jaw bones 4 | 66
Stomach Neoplasms 4 | 300
Sunken eyes 4 | 63
adult high grade glioma 4 | 3,801
ductal carcinoma in situ 4 | 1,745
oligodendroglioma 4 | 2,850
Acquired scoliosis 3 | 281
Anemia 3 | 365
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Blepharoptosis 3 | 231
Brachydactyly 3 | 156
Broad flat nasal bridge 3 | 236
Bushy eyebrows 3 | 49
Byzanthine arch palate 3 | 194
Carcinoma, Squamous Cell 3 | 110
Cognitive delay 3 | 608
Colorectal Neoplasms 3 | 243
Congenital Epicanthus 3 | 177
Congenital deafness 3 | 185
Curvature of spine 3 | 282
Deafness 3 | 198
Downward slant of palpebral fissure 3 | 158
Epilepsy 3 | 792
Frontal bossing 3 | 157
Global developmental delay 3 | 608
Hearing Loss, Partial 3 | 185
Hereditary hemorrhagic telangiectasia 3 | 13
Hypoplastic iliac wing 3 | 19
Immune system cancer 3 | 140
Kidney Diseases 3 | 114
Low set ears 3 | 181
Lymphoid leukemia 3 | 160
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Obesity 3 | 678
Orbital separation excessive 3 | 244
Patent ductus arteriosus 3 | 90
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Simple syndactyly of toes, first web space 3 | 23
Small head 3 | 374
Squamous cell carcinoma 3 | 129
Strabismus 3 | 270
Syndactyly 3 | 88
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
hearing impairment 3 | 199
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Transcription Factor 6 | 1,400
Kinase 3 | 634
Epigenetic 2 | 242
Non-IDG 2 | 12,091

PathwayCommons: inoh Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Zinc finger protein 423 ZNF423 Tbio Transcription Factor -1.62303 45.3 77
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
Mothers against decapentaplegic homolog 7 SMAD7 Tbio Transcription Factor -2.81953 638.7 387
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749