Development Level

Tbio 25 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal heart morphology 3 | 162
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal brain morphology 1 | 13
abnormal kidney morphology 1 | 65
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
edema 1 | 59
hydroencephaly 1 | 14
hyperactivity 1 | 148
increased mean corpuscular vol... 1 | 92
short tibia 1 | 97
small heart 1 | 10

Disease

Carcinoma 22 | 11,493
Cancer 16 | 2,499
psoriasis 15 | 6,694
Osteoporosis 8 | 363
glioblastoma 8 | 5,792
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
interstitial cystitis 7 | 2,312
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
astrocytic glioma 5 | 2,597
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
Juvenile osteoporosis 4 | 4
Osteoporosis, Juvenile 4 | 4
Schizophrenia 4 | 1,160
Short stature 4 | 531
Tooth agenesis 4 | 44
adrenocortical carcinoma 4 | 1,428
oligodendroglioma 4 | 2,850
osteoporosis-pseudoglioma syndrome 4 | 9
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Bladder exstrophy 3 | 32
Bone pain 3 | 42
Cleft Lip 3 | 141
Cleft Palate 3 | 271
Collapse of vertebra 3 | 14
Compression fracture of vertebral column 3 | 14
Congenital diaphragmatic hernia 3 | 67
Female Urogenital Diseases 3 | 18
Frequent fractures 3 | 53
Gait abnormality 3 | 135
Heart conduction disease 3 | 83
Hypodontia 3 | 81
Increased fracture rate 3 | 53
Kidney cancer 3 | 2,613
Obesity 3 | 678
Oligodontia 3 | 24
Parkinson's disease 3 | 392
Varying degree of multiple fractures 3 | 53
adult high grade glioma 3 | 3,801
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
malignant mesothelioma 3 | 3,232
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
primitive neuroectodermal tumor 3 | 3,035
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Broad flat nasal bridge 2 | 236
Chronic obstructive pulmonary disease 2 | 184
Cleft palate with cleft lip 2 | 23
Decreased projection of maxilla 2 | 66
Decreased size of teeth 2 | 62
Deficiency of upper jaw bones 2 | 66
Endometriosis 2 | 540
Fractures, Bone 2 | 13
Fuhrmann syndrome 2 | 7
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Mammary Neoplasms 2 | 425
Maxillary retrognathia 2 | 66
Microdontia (disorder) 2 | 59
Nasal bridge wide 2 | 236
Oral cleft 2 | 18
Osteogenesis imperfecta 2 | 34
Penile hypospadias 2 | 106
Prostatic Neoplasms 2 | 495
Retrusion of upper jaw bones 2 | 66
Syndactyly of the toes 2 | 45
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Ventricular Septal Defects 2 | 119
acute myeloid leukemia 2 | 783
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
inflammatory breast cancer 2 | 286
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010

Tissue

Female tissues 28 | 17,400
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Nervous System 27 | 16,725
Blood and immune system 26 | 16,909
Male tissues 26 | 17,142
Skin and soft tissues 26 | 17,230
Urinary Tract 25 | 16,678
Liver and Pancreas 23 | 16,750
Respiratory system 21 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 28 | 12,091

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
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http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.76391 516.8 355
Protein Wnt-3a WNT3A Tchem Non-IDG -2.74001 473.8 421
Protein Wnt-10a WNT10A Tbio Non-IDG -2.66153 436.3 118
Low-density lipoprotein receptor-related protein 6 LRP6 Tbio Non-IDG -2.44778 273.2 424
Protein Wnt-4 WNT4 Tbio Non-IDG -2.35896 227.8 288
Dickkopf-related protein 3 DKK3 Tbio Non-IDG -2.26030 168.4 444
Protein Wnt-2 WNT2 Tbio Non-IDG -2.28986 167.8 174