Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal lens morphology 1 | 81
abnormal testis morphology 1 | 43
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 7 | 11,493
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
psoriasis 5 | 6,694
Cancer 4 | 2,499
Immunologic Deficiency Syndromes 4 | 113
Kidney cancer 4 | 2,613
ependymoma 4 | 4,679
oligodendroglioma 4 | 2,850
Autosomal recessive predisposition 3 | 1,442
Hyperhidrosis disorder 3 | 81
Increased sweating 3 | 81
Lymphoma 3 | 81
Sweating 3 | 81
astrocytic glioma 3 | 2,597
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Agammaglobulinemia 2 | 34
Anemia 2 | 365
Arthritis 2 | 290
Arthritis, Rheumatoid 2 | 174
Attention deficit hyperactivity disorder 2 | 278
B-Cell Lymphomas 2 | 12
Constipation 2 | 181
Curvature of spine 2 | 282
Dental abnormalities 2 | 60
Diffuse large B-cell lymphoma 2 | 39
Dyschezia 2 | 135
Edwards syndrome 2 | 17
Epilepsy 2 | 792
Familial primary gastric lymphoma 2 | 4
Fatigue 2 | 182
Fever 2 | 138
Flexion contracture of proximal interphalangeal joint 2 | 75
Gastric lymphoma 2 | 7
Hemoglobin low 2 | 124
Hypohidrotic ectodermal dysplasia 2 | 15
Increased susceptibility to bacterial infections 2 | 42
Infantile onset 2 | 238
Infiltrate of lung 2 | 17
Lymphoma, Large B-Cell, Diffuse 2 | 34
Lymphoma, T-Cell, Cutaneous 2 | 22
MALT lymphoma 2 | 6
Nausea and vomiting 2 | 97
Osteopetrosis 2 | 43
Pick disease 2 | 1,894
Prone to bacterial infection 2 | 42
Recurrent bacterial infection 2 | 42
Recurrent infections 2 | 48
Retinal Detachment 2 | 51
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Short stature 2 | 531
Tooth Abnormalities 2 | 69
Waldenstrons macroglobulinemia 2 | 765
Weight decreased 2 | 103
atypical teratoid / rhabdoid tumor 2 | 5,112
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
ATYPICAL MYCOBACTERIOSIS, FAMILIAL, X-LINKED 1 (disorder) 1 | 1
Abnormal hand morphology 1 | 2
Abnormal pigmentation 1 | 25
Asymmetric growth 1 | 5
Atrophic, patchy alopecia 1 | 1
Ectodermal Dysplasia, Anhidrotic, with Immunodeficiency, Osteopetrosis, and Lymphedema 1 | 1
Ectodermal dysplasia, hypohidrotic, with immune deficiency 1 | 2
Fine hair 1 | 42
Hearing abnormality 1 | 12
Hyperkeratosis 1 | 50
Hypoplasia of nipple 1 | 16
Hypoplastic fingernails 1 | 11
INVASIVE PNEUMOCOCCAL DISEASE, RECURRENT ISOLATED, 2 (disorder) 1 | 1
Immunodeficiency without anhidrotic ectodermal dysplasia 1 | 1
Impaired memory B-cell generation 1 | 3
Incontinentia pigmenti syndrome 1 | 1
Increased IgM levels 1 | 16
Invasive pneumococcal disease, recurrent isolated, 2 1 | 1
Irregular hyperpigmentation 1 | 33
Kyphoscoliosis deformity of spine 1 | 60
Onset of lymphedema around puberty 1 | 21
Oral cleft 1 | 18
Peg shaped front tooth 1 | 6
Peg-shaped incisors 1 | 6
Pointed front tooth 1 | 6
Pointed incisor 1 | 6
Recurrent mycobacterium avium complex infections 1 | 2
Ridged nails 1 | 14
Warts 1 | 10
X- linked recessive 1 | 110
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 5 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB Tchem Kinase -2.93125 790.1 1824
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT1 Tchem Non-IDG -2.41823 254.0 468
Caspase recruitment domain-containing protein 11 CARD11 Tbio Enzyme -2.17228 139.2 235
Ubiquitin-conjugating enzyme E2 N UBE2N Tbio Non-IDG -2.08846 107.8 268
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Protein kinase C theta type PRKCQ Tchem Kinase -1.08459 10.8 592
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.53932 4.30 895