Development Level

Tbio 25 | 10,625
Tchem 3 | 1,890

IMPC Term

preweaning lethality, complete... 2 | 633
short tibia 2 | 82
abnormal embryo size 1 | 112
abnormal heart morphology 1 | 51
decreased caudal vertebrae num... 1 | 49
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased startle reflex 1 | 48
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased cellular hemoglobin ... 1 | 2
increased mean corpuscular vol... 1 | 91

Disease

psoriasis 15 | 6,685
Cancer 13 | 2,346
Osteoporosis 8 | 257
glioblastoma 8 | 5,572
medulloblastoma, large-cell 8 | 6,234
osteosarcoma 8 | 7,933
ovarian cancer 8 | 8,484
interstitial cystitis 7 | 2,299
Breast cancer 6 | 3,094
invasive ductal carcinoma 6 | 2,950
non-small cell lung cancer 6 | 2,798
pilocytic astrocytoma 6 | 3,086
breast carcinoma 5 | 1,614
cutaneous lupus erythematosus 5 | 1,056
cystic fibrosis 5 | 1,665
lung adenocarcinoma 5 | 2,713
lung cancer 5 | 4,466
lung carcinoma 5 | 2,844
pediatric high grade glioma 5 | 2,712
Cleft palate 4 | 125
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
atypical teratoid / rhabdoid tumor 4 | 4,369
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
ulcerative colitis 4 | 2,087
Atopic dermatitis 3 | 944
Carcinoma 3 | 2,147
Cleft Lip 3 | 91
Female Urogenital Diseases 3 | 18
Heart conduction disease 3 | 65
Hyperostosis 3 | 16
Peripheral Neuropathy 3 | 303
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,475
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 2,254
posterior fossa group A ependymoma 3 | 1,511
primitive neuroectodermal tumor 3 | 3,031
Craniodiaphyseal dysplasia 2 | 3
Crohn's disease 2 | 304
Endometriosis 2 | 535
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 2 | 12
Mammary Neoplasms 2 | 410
Osteogenesis imperfecta 2 | 34
Parkinson's disease 2 | 364
Tooth agenesis 2 | 36
Uterine Cervical Neoplasm 2 | 21
acute myeloid leukemia 2 | 780
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
group 4 medulloblastoma 2 | 1,875
inflammatory breast cancer 2 | 404
malignant mesothelioma 2 | 3,162
non primary Sjogren syndrome sicca 2 | 840
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Amenorrhea 1 | 60
Androgenic alopecia 1 | 10
Ankylosing spondylitis 1 | 138
Barrett's esophagus 1 | 183
Blindness 1 | 84
Celiac disease 1 | 112
Colorectal Neoplasms 1 | 217
Connective tissue disease 1 | 59
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 1 | 3
Epithelial ovarian cancer 1 | 19
Esophageal Neoplasms 1 | 67
Fibroid Tumor 1 | 6
Frontotemporal dementia 1 | 41
Genitourinary Neoplasms 1 | 3
Hypohidrotic ectodermal dysplasia 1 | 13
Hypotrichosis 1 | 29
Kidney Diseases 1 | 86
Lung Neoplasms 1 | 171
Lymphoid leukemia 1 | 69
Motor neuron disease 1 | 39
Nasopharyngeal Neoplasms 1 | 8
Neoplastic Cell Transformation 1 | 81
Osteopetrosis 1 | 40
Palmoplantar keratosis 1 | 36
Parkinson Disease 1 | 102
Pleomorphic adenoma 1 | 18
Premature ovarian failure 1 | 64
Renal agenesis 1 | 25
Retinopathy of prematurity 1 | 21
Robinow syndrome 1 | 12
Salivary Gland Neoplasms 1 | 45
Scheuermann's disease 1 | 10
axial spondyloarthropathy 1 | 28
facioscapulohumeral dystrophy 1 | 286
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
nail-patella syndrome 1 | 16
sarcoidosis 1 | 358

Tissue

Digestive Tract 28 | 18,473
Endocrine System 28 | 18,512
Female tissues 28 | 18,647
Male tissues 28 | 17,969
Nervous System 28 | 18,561
Respiratory system 28 | 17,484
Skin and soft tissues 28 | 18,115
Urinary Tract 28 | 18,444
Blood and immune system 27 | 17,995
Liver and Pancreas 27 | 18,136
Cardiovascular System 26 | 17,958

Target Family

Non-IDG 28 | 11,971

PathwayCommons: inoh Pathway

Xenopus axis formation Wnt sig... 28 | 28
Drosophila Toll-like receptor ... 236 | 236
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
B cell receptor signaling path... 60 | 60
Tryptophan degradation ( Trypt... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
TGF beta receptor complex degr... 48 | 48
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
TGF beta receptor I degradatio... 43 | 43
Inositol phosphate metabolism ... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 38 | 38
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.06756 1202.0 278
Kremen protein 2 KREMEN2 Tbio Non-IDG -0.72771 5.50 84
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.70833 552.4 624
Protein Wnt-6 WNT6 Tbio Non-IDG -1.60144 43.1 156
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.71893 492.7 294
Protein Wnt-5a WNT5A Tbio Non-IDG -2.69880 587.4 277
Wnt inhibitory factor 1 WIF1 Tbio Non-IDG -2.04106 130.3 298
Protein Wnt-8b WNT8B Tbio Non-IDG -1.33309 19.1 144
Protein Wnt-2b WNT2B Tbio Non-IDG -1.68954 53.4 146
Low-density lipoprotein receptor-related protein 6 LRP6 Tbio Non-IDG -2.38398 249.1 270