Development Level

Tbio 25 | 10,625
Tchem 23 | 1,890
Tclin 11 | 602
Tdark 1 | 7,003

IMPC Term

abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
decreased mean corpuscular vol... 2 | 50
increased red blood cell distr... 2 | 21
preweaning lethality, complete... 2 | 633
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
cataract 1 | 26
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
increased circulating alkaline... 1 | 119
increased circulating insulin ... 1 | 2
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38

Disease

psoriasis 35 | 6,685
lung cancer 26 | 4,466
ovarian cancer 25 | 8,484
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
osteosarcoma 22 | 7,933
interstitial cystitis 20 | 2,299
Cancer 19 | 2,346
medulloblastoma, large-cell 18 | 6,234
invasive ductal carcinoma 17 | 2,950
lung carcinoma 17 | 2,844
ductal carcinoma in situ 16 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
lung adenocarcinoma 14 | 2,713
non-small cell lung cancer 14 | 2,798
pituitary cancer 14 | 1,972
ulcerative colitis 14 | 2,087
Prostatic Neoplasms 13 | 471
glioblastoma 13 | 5,572
breast carcinoma 12 | 1,614
colon cancer 11 | 1,475
cutaneous lupus erythematosus 11 | 1,056
malignant mesothelioma 11 | 3,162
Liver disease 10 | 219
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
pancreatic cancer 10 | 2,300
tuberculosis 10 | 1,557
adrenocortical carcinoma 9 | 1,427
atypical teratoid / rhabdoid tumor 9 | 4,369
posterior fossa group A ependymoma 9 | 1,511
Atopic dermatitis 8 | 944
Mammary Neoplasms 8 | 410
cystic fibrosis 8 | 1,665
diabetes mellitus 8 | 1,663
Alcohol dependence 7 | 107
Autistic Disorder 7 | 320
Breast cancer 7 | 3,094
Schizophrenia 7 | 501
active Crohn's disease 7 | 918
adult high grade glioma 7 | 2,148
esophageal adenocarcinoma 7 | 737
oligodendroglioma 7 | 2,849
pilocytic astrocytoma 7 | 3,086
primitive neuroectodermal tumor 7 | 3,031
Endometriosis 6 | 535
Epilepsy 6 | 346
Major Depressive Disorder 6 | 106
Parkinson's disease 6 | 364
chronic rhinosinusitis 6 | 512
group 3 medulloblastoma 6 | 2,254
nephrosclerosis 6 | 329
pediatric high grade glioma 6 | 2,712
primary Sjogren syndrome 6 | 789
Alzheimer's disease 5 | 644
Drug-Induced Liver Injury 5 | 118
Hypertension 5 | 287
Obesity 5 | 616
Parkinson Disease 5 | 102
Peripheral Neuropathy 5 | 303
Succinic semialdehyde dehydrogenase deficiency 5 | 16
acute myeloid leukemia 5 | 780
aldosterone-producing adenoma 5 | 664
group 4 medulloblastoma 5 | 1,875
substance-related disorder 5 | 105
Adverse reaction to drug 4 | 54
Asthma 4 | 349
Attention deficit hyperactivity disorder 4 | 156
Cardiomegaly 4 | 66
Colorectal Neoplasms 4 | 217
Human immunodeficiency virus infection 4 | 6
Hypertensive disease 4 | 193
Kidney disease 4 | 396
Liver Cirrhosis, Experimental 4 | 108
Lung Neoplasms 4 | 171
Male infertility 4 | 170
Pellagra 4 | 25
Toxic encephalopathy 4 | 131
acute quadriplegic myopathy 4 | 1,157
ependymoma 4 | 2,514
fibroadenoma 4 | 557
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
inflammatory breast cancer 4 | 404
juvenile dermatomyositis 4 | 1,189
nasopharyngeal carcinoma 4 | 1,056
Coronary artery disease 3 | 240
Dementia 3 | 129
Disease Progression 3 | 125
Malaria 3 | 140
Pick disease 3 | 1,893
Stomach Neoplasms 3 | 282
adrenocortical adenoma 3 | 134
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
head and neck cancer 3 | 270
non-small cell lung carcinoma 3 | 413
periodontitis 3 | 269
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 60 | 18,473
Endocrine System 60 | 18,512
Female tissues 60 | 18,647
Liver and Pancreas 60 | 18,136
Nervous System 60 | 18,561
Skin and soft tissues 60 | 18,115
Urinary Tract 60 | 18,444
Blood and immune system 59 | 17,995
Cardiovascular System 59 | 17,958
Male tissues 59 | 17,969
Respiratory system 59 | 17,484

Target Family

Enzyme 40 | 4,146
Non-IDG 19 | 11,971
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

Tryptophan degradation ( Trypt... 60 | 60
Drosophila Toll-like receptor ... 236 | 236
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
B cell receptor signaling path... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
TGF beta receptor complex degr... 48 | 48
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
TGF beta receptor I degradatio... 43 | 43
Inositol phosphate metabolism ... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 38 | 38
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Xenopus axis formation Wnt sig... 28 | 28
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.98787 974.3 154
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.73036 583.4 632
Retina-specific copper amine oxidase AOC2 Tchem Enzyme -2.24632 179.3 53
Cytochrome P450 4B1 CYP4B1 Tbio Non-IDG -1.77340 65.4 88
Cytochrome P450 2J2 CYP2J2 Tchem Non-IDG -2.03738 133.3 162
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.26785 189.3 264
Transcriptional repressor NF-X1 NFX1 Tbio Transcription Factor -1.29370 22.4 102