Development Level

Tbio 9 | 10,625
Tchem 5 | 1,890

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal lens morphology 1 | 73
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to t... 1 | 187
increased NK cell number 1 | 19
increased body weight 1 | 42
increased fasted circulating g... 1 | 68
polydactyly 1 | 22

Disease

psoriasis 10 | 6,685
glioblastoma 8 | 5,572
medulloblastoma, large-cell 8 | 6,234
ovarian cancer 8 | 8,484
osteosarcoma 7 | 7,933
lung cancer 6 | 4,466
Cancer 5 | 2,346
atypical teratoid / rhabdoid tumor 5 | 4,369
juvenile dermatomyositis 5 | 1,189
malignant mesothelioma 5 | 3,162
Rheumatoid Arthritis 4 | 1,160
astrocytic glioma 4 | 2,241
dermatomyositis 4 | 933
group 4 medulloblastoma 4 | 1,875
lung carcinoma 4 | 2,844
pediatric high grade glioma 4 | 2,712
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 1,557
Arthritis 3 | 248
Asthma 3 | 349
Coronary artery disease 3 | 240
IGA Glomerulonephritis 3 | 454
Meningitis 3 | 46
Peritonitis 3 | 37
Pick disease 3 | 1,893
Pneumonia 3 | 133
Prostatic Neoplasms 3 | 471
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
cutaneous lupus erythematosus 3 | 1,056
diabetes mellitus 3 | 1,663
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
oligodendroglioma 3 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Colorectal Neoplasms 2 | 217
Duchenne muscular dystrophy 2 | 602
Gaucher disease type 3 2 | 76
Hypersensitivity reaction type II disease 2 | 235
Hypohidrotic ectodermal dysplasia 2 | 13
Hypoxia-Ischemia, Brain 2 | 5
Inflammation 2 | 109
Inflammatory bowel disease 2 | 142
Influenza 2 | 142
Keratitis 2 | 42
Liver disease 2 | 219
Malaria 2 | 140
Mastitis 2 | 48
Metabolic syndrome X 2 | 155
Multiple Sclerosis 2 | 498
Neoplasm Invasiveness 2 | 127
Neoplasm Metastasis 2 | 138
Obesity 2 | 616
Perinatal necrotizing enterocolitis 2 | 18
Reperfusion Injury 2 | 84
Sepsis 2 | 21
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
cystic fibrosis 2 | 1,665
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
periodontitis 2 | 269
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,031
ulcerative colitis 2 | 2,087
Adenosine deaminase deficiency 1 | 3
Brain disease 1 | 83
Colitis 1 | 46
Gout 1 | 93
IRAK4 Deficiency 1 | 1
Immune system cancer 1 | 38
Invasive Pneumococcal Disease, Recurrent Isolated, 1 1 | 2
Job's syndrome 1 | 4
Leishmaniasis 1 | 49
Leptospirosis 1 | 17
Liver Cirrhosis, Experimental 1 | 108
Lung Neoplasms 1 | 171
Lymphoma, Follicular 1 | 20
Melanoma 1 | 261
Neonatal abstinence syndrome 1 | 9
Osteopetrosis 1 | 40
Osteoporosis 1 | 257
Portal hypertension 1 | 21
Renal Cell Carcinoma 1 | 199
Weight Gain 1 | 87
active ulcerative colitis 1 | 477
atypical teratoid/rhabdoid tumor 1 | 1,095
facioscapulohumeral dystrophy 1 | 286
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
limb girdle muscular dystrophy 2A 1 | 156
ovarian neoplasm 1 | 97

Tissue

Blood and immune system 14 | 17,995
Cardiovascular System 14 | 17,958
Digestive Tract 14 | 18,473
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Liver and Pancreas 14 | 18,136
Male tissues 14 | 17,969
Nervous System 14 | 18,561
Respiratory system 14 | 17,484
Skin and soft tissues 14 | 18,115
Urinary Tract 14 | 18,444

Target Family

Non-IDG 9 | 11,971
Kinase 4 | 634
Enzyme 1 | 4,146

PathwayCommons: inoh Pathway

Toll-like receptor signaling p... 14 | 14
Drosophila Toll-like receptor ... 236 | 236
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
B cell receptor signaling path... 60 | 60
Tryptophan degradation ( Trypt... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
TGF beta receptor complex degr... 48 | 48
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
TGF beta receptor I degradatio... 43 | 43
Inositol phosphate metabolism ... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 38 | 38
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Xenopus axis formation Wnt sig... 28 | 28
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.83055 69.0 145
Toll-interacting protein TOLLIP Tbio Non-IDG -1.78649 72.7 353
Ubiquitin-conjugating enzyme E2 N UBE2N Tchem Non-IDG -2.02460 99.0 237
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.69962 490.7 314
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.63770 438.1 349
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.17898 1606.1 561
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.27150 16.3 155
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.35481 28.0 678
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.21875 182.4 530