Development Level

Tchem 5 | 1,890
Tbio 3 | 10,625
Tclin 2 | 602

IMPC Phenotype

abnormal gait 1 | 51
decreased body weight 1 | 174
decreased total body fat amoun... 1 | 186
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36

Disease

Cancer 8 | 2,346
ovarian cancer 8 | 8,491
psoriasis 7 | 6,685
glioblastoma 6 | 5,572
Vascular disease 5 | 281
atypical teratoid / rhabdoid tumor 5 | 4,369
medulloblastoma, large-cell 5 | 6,234
pituitary cancer 5 | 1,972
Juvenile arthritis 4 | 124
Parkinson's disease 4 | 364
Reperfusion Injury 4 | 84
Toxic encephalopathy 4 | 131
acute myeloid leukemia 4 | 785
aldosterone-producing adenoma 4 | 664
group 4 medulloblastoma 4 | 1,875
hepatocellular carcinoma 4 | 550
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
lung cancer 4 | 4,473
lung carcinoma 4 | 2,844
osteosarcoma 4 | 7,933
primitive neuroectodermal tumor 4 | 3,031
Alzheimer's disease 3 | 644
Arthritis 3 | 248
Brain Ischemia 3 | 87
Epilepsy 3 | 346
Eye disease 3 | 55
Intellectual disability 3 | 573
Kidney disease 3 | 397
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,170
Waldenstrons macroglobulinemia 3 | 764
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
breast carcinoma 3 | 1,614
chronic lymphosyte leukemia 3 | 232
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
gastric cancer 3 | 436
inflammatory breast cancer 3 | 404
lung adenocarcinoma 3 | 2,714
malignant mesothelioma 3 | 3,163
medulloblastoma 3 | 1,524
nephrosclerosis 3 | 329
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pilocytic astrocytoma 3 | 3,086
pterygium 3 | 74
subependymal giant cell astrocytoma 3 | 2,287
Brain disease 2 | 84
Cardio-facio-cutaneous syndrome 2 | 6
Cardiofaciocutaneous syndrome 2 | 15
Cardiofaciocutaneous syndrome 1 2 | 4
Cardiomyopathy 2 | 110
Cocaine-Related Disorders 2 | 88
Costello Syndrome 2 | 18
Costello syndrome (disorder) 2 | 7
Gastrointestinal system disease 2 | 50
Heart disease 2 | 279
Heat Stroke 2 | 12
Hyperglycemia 2 | 120
LEOPARD Syndrome 2 | 20
Liver carcinoma 2 | 217
Lung Neoplasms 2 | 171
Lung disease 2 | 136
Malignant Melanoma with BRAF V600E Mutation 2 | 4
Malignant Melanoma with BRAF V600K Mutation 2 | 2
Mammary Neoplasms 2 | 410
Melanoma 2 | 261
Metastatic malignant melanoma 2 | 9
Morphine dependence 2 | 19
Multiple myeloma 2 | 1,327
Neoplastic Cell Transformation 2 | 81
Noonan Syndrome 2 | 33
Osteoporosis 2 | 259
Pick disease 2 | 1,893
Precancerous Conditions 2 | 69
Status Epilepticus 2 | 85
Stomach Neoplasms 2 | 282
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
ependymoma 2 | 2,514
fibroadenoma 2 | 557
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
juvenile dermatomyositis 2 | 1,189
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
spina bifida 2 | 1,064
tuberculosis 2 | 1,563
ulcerative colitis 2 | 2,087
Cerebrovascular disease 1 | 231
Hypertension 1 | 293
Hypertensive disease 1 | 193
Metabolic syndrome X 1 | 155

Tissue

Blood and immune system 10 | 17,994
Cardiovascular System 10 | 17,957
Digestive Tract 10 | 18,472
Endocrine System 10 | 18,511
Female tissues 10 | 18,646
Liver and Pancreas 10 | 18,135
Male tissues 10 | 17,968
Nervous System 10 | 18,560
Respiratory system 10 | 17,483
Skin and soft tissues 10 | 18,114
Urinary Tract 10 | 18,443

Target Family

Kinase 5 | 634
Transcription Factor 5 | 1,400

PathwayCommons: inoh Pathway

JNK cascade ( CD4 T cell recep... 10 | 10
Drosophila Toll-like receptor ... 235 | 235
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
B cell receptor signaling path... 60 | 60
Tryptophan degradation ( Trypt... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
TGF beta receptor complex degr... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
Inositol phosphate metabolism ... 42 | 42
TGF beta receptor I degradatio... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 37 | 37
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Xenopus axis formation Wnt sig... 28 | 28
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein fosB FOSB Tbio Transcription Factor -2.64139 409.7 306
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.27384 181.6 339
Fos-related antigen 2 FOSL2 Tbio Transcription Factor -2.14352 120.7 388
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.36131 214.3 211
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.79775 57.0 688
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.04744 808.6 1868
Mitogen-activated protein kinase 8 MAPK8 Tchem Kinase -3.77749 5333.9 1016
Mitogen-activated protein kinase 9 MAPK9 Tchem Kinase -2.65358 339.1 515
Transcription factor AP-1 JUN Tchem Transcription Factor -3.82163 5981.8 2262