Development Level

Tbio 9 | 10,625
Tclin 4 | 602
Tdark 3 | 7,003
Tchem 1 | 1,890

IMPC Phenotype

abnormal coping response 1 | 12
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
preweaning lethality, incomple... 1 | 260

Disease

Cancer 7 | 2,346
Hepatitis B 5 | 103
Hepatitis C 5 | 90
medulloblastoma, large-cell 5 | 6,234
osteosarcoma 5 | 7,933
ovarian cancer 5 | 8,491
Hepatitis 4 | 61
Influenza 4 | 142
Multiple Sclerosis 4 | 498
Polycythemia Vera 4 | 24
Rheumatoid Arthritis 4 | 1,170
glioblastoma 4 | 5,572
psoriasis 4 | 6,685
Anemia 3 | 252
Carcinoma 3 | 2,147
Hypersensitivity reaction type II disease 3 | 235
Liver Cirrhosis 3 | 101
Multiple myeloma 3 | 1,327
Thrombocytopenia 3 | 105
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
lung cancer 3 | 4,473
pancreatic cancer 3 | 2,300
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Chronic hepatitis C 2 | 12
Chronic type B viral hepatitis 2 | 2
Cryoglobulinemia 2 | 15
Diarrhea 2 | 155
Down syndrome 2 | 548
Encephalitis 2 | 54
Hepatitis D 2 | 10
Leukopenia 2 | 42
Melanoma 2 | 261
Muscle Weakness 2 | 92
Pancreatic Neoplasm 2 | 79
Relapsing remitting multiple sclerosis 2 | 14
Renal Cell Carcinoma 2 | 199
Severe acute respiratory syndrome 2 | 26
Stomatitis 2 | 19
astrocytoma 2 | 1,493
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
pilocytic astrocytoma 2 | 3,086
systemic lupus erythematosus 2 | 172
Achondroplasia 1 | 20
Acquired immunodeficiency syndrome 1 | 164
Adult T-Cell Lymphoma/Leukemia 1 | 30
Aicardi-Goutieres syndrome 1 | 18
Anogenital venereal wart 1 | 8
Anorexia 1 | 15
Anxiety Disorders 1 | 37
Arthritis, Experimental 1 | 39
Biliary cirrhosis 1 | 33
Candidiasis 1 | 48
Candidiasis, Chronic Mucocutaneous 1 | 7
Connective tissue disease 1 | 59
Cortical blindness 1 | 15
Crimean-Congo hemorrhagic fever 1 | 10
Diabetes Mellitus, Insulin-Dependent 1 | 77
Fatty Liver 1 | 48
Hairy Cell Leukemia 1 | 6
Hepatitis B, Chronic 1 | 15
Hepatitis, Chronic 1 | 22
Herpes simplex 1 | 19
Hodgkin Disease 1 | 16
Hypertriglyceridemia 1 | 18
Immunodeficiency 35 1 | 1
Intestinal perforation 1 | 6
Job's syndrome 1 | 4
Juvenile rheumatoid factor-negative polyarthritis 1 | 9
Liver Cirrhosis, Experimental 1 | 108
Liver disease 1 | 219
Lymphoma, Primary Cutaneous Anaplastic Large Cell 1 | 2
Lymphomatoid Papulosis 1 | 2
Myocardial Infarction 1 | 126
Oligoarticular juvenile arthritis 1 | 9
Pain 1 | 70
Paranoia 1 | 8
Peyronie's disease 1 | 8
Pityriasis rubra pilaris 1 | 5
Retinal Diseases 1 | 21
Retinal detachment 1 | 33
Sepsis 1 | 21
Skin disease 1 | 65
Squamous cell carcinoma 1 | 96
St. Louis encephalitis 1 | 5
Stevens-Johnson syndrome 1 | 91
Subacute sclerosing panencephalitis 1 | 10
Substance Withdrawal Syndrome 1 | 55
Susceptibility to viral and mycobacterial infections 1 | 11
Thanatophoric dysplasia 1 | 5
Thyroid Neoplasm 1 | 33
Thyroiditis 1 | 25
Type 1 diabetes mellitus 1 | 104
Tyrosine Kinase 2 Deficiency 1 | 1
Weight decreased 1 | 18
chronic mucocutaneous candidiasis 1 | 7

Tissue

Nervous System 17 | 18,560
Female tissues 16 | 18,646
Digestive Tract 15 | 18,472
Urinary Tract 15 | 18,443
Skin and soft tissues 14 | 18,114
Blood and immune system 11 | 17,994
Endocrine System 11 | 18,511
Cardiovascular System 10 | 17,957
Liver and Pancreas 9 | 18,135
Respiratory system 8 | 17,483
Male tissues 6 | 17,968

Target Family

Non-IDG 14 | 11,969
Kinase 2 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

IFN alpha signaling pathway(JA... 17 | 17
Drosophila Toll-like receptor ... 235 | 235
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
B cell receptor signaling path... 60 | 60
Tryptophan degradation ( Trypt... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
TGF beta receptor complex degr... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
Inositol phosphate metabolism ... 42 | 42
TGF beta receptor I degradatio... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 37 | 37
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Xenopus axis formation Wnt sig... 28 | 28
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal transducer and activator of transcription 1-alpha/beta STAT1 Tchem Transcription Factor -3.29893 1889.3 1357
Interferon alpha-8 IFNA8 Tbio Non-IDG -1.38242 22.0 54
Interferon alpha/beta receptor 1 IFNAR1 Tclin Non-IDG -2.61876 407.4 484
Tyrosine-protein kinase JAK1 JAK1 Tclin Kinase -2.73793 446.6 400
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.90656 74.0 225
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.37719 239.8 41
Interferon alpha-14 IFNA14 Tdark Non-IDG -0.36715 2.01 45
Interferon alpha-5 IFNA5 Tbio Non-IDG -1.77269 51.4 127
Interferon alpha-21 IFNA21 Tbio Non-IDG -0.88029 5.76 74
Interferon alpha-7 IFNA7 Tdark Non-IDG -0.67991 3.90 46