Development Level

Tdark 38 | 7,003
Tchem 9 | 1,890
Tbio 8 | 10,625
Tclin 5 | 602

IMPC Term

decreased body weight 2 | 174
decreased circulating creatini... 2 | 31
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal femur morphology 1 | 14
decreased B cell number 1 | 30
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating triglyce... 1 | 83
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
increased IgG1 level 1 | 1
increased T cell number 1 | 15
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 23 | 7,933
psoriasis 18 | 6,685
interstitial cystitis 17 | 2,299
ulcerative colitis 15 | 2,087
Cancer 14 | 2,346
lung cancer 14 | 4,473
ovarian cancer 13 | 8,492
tuberculosis 12 | 1,563
primary Sjogren syndrome 11 | 789
medulloblastoma, large-cell 10 | 6,234
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,714
pancreatic cancer 9 | 2,300
periodontitis 9 | 269
cutaneous lupus erythematosus 8 | 1,056
Multiple myeloma 7 | 1,328
chronic lymphosyte leukemia 7 | 232
lung carcinoma 7 | 2,844
subependymal giant cell astrocytoma 7 | 2,287
Carcinoma 6 | 2,147
glioblastoma 6 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
nasopharyngeal carcinoma 6 | 1,056
non-small cell lung cancer 6 | 2,798
non-small cell lung carcinoma 6 | 413
Agammaglobulinemia 5 | 24
Agammaglobulinemia, non-Bruton type 5 | 8
Diffuse large B-cell lymphoma 5 | 42
Rheumatoid Arthritis 5 | 1,171
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 2,148
cystic fibrosis 5 | 1,670
diabetes mellitus 5 | 1,663
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
juvenile dermatomyositis 5 | 1,189
pilocytic astrocytoma 5 | 3,086
Breast cancer 4 | 3,099
Cherubism 4 | 14
atypical teratoid / rhabdoid tumor 4 | 4,369
colon cancer 4 | 1,475
cystic fibrosis and chronic rhinosinusitis 4 | 213
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
medulloblastoma 4 | 1,524
primary pancreatic ductal adenocarcinoma 4 | 1,271
Acquired immunodeficiency syndrome 3 | 164
Adult T-Cell Lymphoma/Leukemia 3 | 30
Allergic hypersensitivity disease 3 | 123
Blastic phase chronic myeloid leukemia 3 | 58
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Chronic obstructive pulmonary disease 3 | 147
Chronic phase chronic myeloid leukemia 3 | 45
Down syndrome 3 | 548
Kidney disease 3 | 397
Multiple Sclerosis 3 | 498
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 3 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 3 | 47
Stomach Neoplasms 3 | 282
acute myeloid leukemia 3 | 785
esophageal adenocarcinoma 3 | 737
malignant mesothelioma 3 | 3,163
oligodendroglioma 3 | 2,849
pancreatic carcinoma 3 | 567
primitive neuroectodermal tumor 3 | 3,031
sarcoidosis 3 | 368
spina bifida 3 | 1,064
Amebiasis 2 | 22
Anemia 2 | 252
Arthritis 2 | 248
Atopic dermatitis 2 | 944
Carcinoma of colon 2 | 32
Collagen disease 2 | 25
Colorectal Neoplasms 2 | 217
Endometrial cancer 2 | 32
Hypersensitivity reaction type II disease 2 | 235
Influenza 2 | 142
Kidney cancer 2 | 121
Leukopenia 2 | 42
Lupus erythematosus 2 | 80
Mammary Neoplasms 2 | 410
Myositis 2 | 24
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Renal Cell Carcinoma 2 | 199
Schizophrenia 2 | 503
Severe Combined Immunodeficiency 2 | 46
Thrombocytopenia 2 | 105
Urinary bladder cancer 2 | 34
Urticaria 2 | 53
astrocytoma 2 | 1,493
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 967
ependymoma 2 | 2,514
mucosa-associated lymphoid tissue lymphoma 2 | 480
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 49 | 17,995
Digestive Tract 49 | 18,473
Female tissues 49 | 18,647
Respiratory system 49 | 17,484
Skin and soft tissues 49 | 18,115
Liver and Pancreas 48 | 18,136
Urinary Tract 48 | 18,444
Cardiovascular System 47 | 17,958
Endocrine System 46 | 18,512
Nervous System 46 | 18,561
Male tissues 44 | 17,969

Target Family

Non-IDG 49 | 11,969
Kinase 9 | 634
Enzyme 2 | 4,146

PathwayCommons: inoh Pathway

B cell receptor signaling path... 60 | 60
Drosophila Toll-like receptor ... 236 | 236
Heterotrimeric GPCR signaling ... 235 | 235
Heterotrimeric GPCR signaling ... 233 | 233
Heterotrimeric GPCR signaling ... 224 | 224
Heterotrimeric GTP-binding pro... 224 | 224
Heterotrimeric GPCR signaling ... 223 | 223
Heterotrimeric GTP-binding pro... 223 | 223
VEGF signaling pathway ( VEGF ... 183 | 183
Positive regulation of (Transc... 178 | 178
AKT(PKB)-Bad signaling ( EPO s... 173 | 173
AKT(PKB)-Bad signaling ( IL-7 ... 173 | 173
Integrin signaling pathway ( I... 123 | 123
JAK-STAT pathway and regulatio... 96 | 96
Purine nucleotides and Nucleos... 85 | 85
Tryptophan degradation ( Trypt... 60 | 60
Insulin receptor signaling (Ma... 58 | 58
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Canonical Wnt signaling pathwa... 56 | 56
Insulin receptor signaling ( I... 55 | 55
TGF-beta_super_family_signalin... 51 | 51
Mammalian Wnt signaling pathwa... 49 | 49
TGF beta receptor complex degr... 48 | 48
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Canonical)... 47 | 47
Signaling with Wnt (Mammal) ( ... 47 | 47
Heterotrimeric GPCR signaling ... 45 | 45
FGF signaling pathway ( FGF si... 44 | 44
T cell receptor signaling path... 43 | 43
TGF beta receptor I degradatio... 43 | 43
Inositol phosphate metabolism ... 42 | 42
CD4 T cell receptor signaling ... 40 | 40
Cytokine receptor degradation ... 40 | 40
Negative regulation of (Phosph... 40 | 40
T cell receptor signaling (PLC... 40 | 40
SnoN degradation signaling ( T... 38 | 38
T cell receptor signaling (PLC... 37 | 37
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha i GDP-GTP exchange sig... 36 | 36
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
G alpha s GDP-GTP exchange sig... 35 | 35
BMP signaling pathway ( TGF-be... 34 | 34
HGF signaling pathway ( HGF si... 30 | 30
Pyrimidine Nucleotides and Nuc... 30 | 30
Arginine and Proline metabolis... 29 | 29
PDGF signaling pathway (Mammal... 29 | 29
Xenopus axis formation Wnt sig... 28 | 28
Glycine and Serine metabolism ... 27 | 27
IGF1 signaling pathway ( IGF1 ... 27 | 27
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Stabilization and accumulation... 24 | 24
Prostaglandin and Leukotriene ... 22 | 22
Fas signaling pathway ( Fas si... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (G alph... 21 | 21
Negative regulation of (transc... 21 | 21
FGF8 signaling pathway(Mouse) ... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of (G alph... 20 | 20
Negative regulation of heterot... 20 | 20
Canonical Notch signaling path... 19 | 19
IFN alpha signaling pathway((J... 19 | 19
Signaling with Wnt (Xenopus) (... 19 | 19
Toll-like receptor signaling p... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Canonic... 19 | 19
Wnt secretory pathway (Mammal)... 19 | 19
FGF8 signaling pathway(Xenopus... 18 | 18
Heterotrimeric GPCR signaling ... 18 | 18
Histidine degradation ( Histid... 18 | 18
IFN alpha signaling pathway(JA... 18 | 18
Nicotinate and Nicotinamide me... 18 | 18
PKA activation signaling ( GPC... 18 | 18
PKA activation signaling ( GPC... 18 | 18
Ci/Gli processing signaling ( ... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
ERK cascade ( FGF8 signaling (... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
IFN alpha signaling pathway(JA... 17 | 17
Folate metabolism ( Folate met... 16 | 16
JNK cascade ( IL-1 signaling p... 16 | 16
Methionine and Cysteine metabo... 16 | 16
NGF signaling pathway ( NGF si... 16 | 16
Valine,Leucine and Isoleucine ... 16 | 16
p38 cascade ( IL-1 signaling p... 16 | 16
IL-1_signaling(through_IKK-NFk... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein kinase C beta type PRKCB Tchem Kinase -1.97915 83.5 530
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-16 IGKV1-16 Tdark Non-IDG 0.00000 0
B-cell linker protein BLNK Tbio Non-IDG -2.75965 568.2 429
Ig lambda-1 chain C regions IGLC1 Tbio Non-IDG -1.81183 228.7 0
B-lymphocyte antigen CD19 CD19 Tclin Non-IDG -3.51748 3029.8 2072
B-cell antigen receptor complex-associated protein beta chain CD79B Tbio Non-IDG -2.51382 315.4 542
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.49806 301.3 641
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0