Development Level

Tdark 3 | 7,003
Tbio 2 | 10,625

Disease

Microcephaly 4 | 149
Pontocerebellar hypoplasia 4 | 29
Deglutition Disorders 3 | 4
Intellectual disability 3 | 573
Movement Disorders 3 | 21
Neurodegenerative disease 3 | 383
Pontocerebellar Hypoplasia Type 2 3 | 4
Vision Disorders 3 | 5
osteosarcoma 3 | 7,933
ovarian cancer 3 | 8,484
atypical teratoid / rhabdoid tumor 2 | 4,369
glioblastoma 2 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
medulloblastoma, large-cell 2 | 6,234
Attention deficit hyperactivity disorder 1 | 156
Breast cancer 1 | 3,094
Megalocornea 1 | 15
Obesity 1 | 616
Olivopontocerebellar hypoplasia 1 | 1
Olivopontocerebellar hypoplasia, fetal-onset 1 | 1
PONTOCEREBELLAR HYPOPLASIA TYPE 4 (disorder) 1 | 1
Pick disease 1 | 1,893
Pontocerebellar Hypoplasia Type 1 1 | 5
Pontocerebellar Hypoplasia Type 2A 1 | 1
Pontocerebellar Hypoplasia Type 2B 1 | 1
Pontocerebellar Hypoplasia Type 2C 1 | 1
Primary microcephaly 1 | 6
Prostate cancer 1 | 172
Seizure Adverse Event 1 | 19
Weight Gain 1 | 87
X-linked cerebral adrenoleukodystrophy 1 | 115
astrocytoma 1 | 1,493
colon cancer 1 | 1,475
group 3 medulloblastoma 1 | 2,254
lung cancer 1 | 4,466
malignant mesothelioma 1 | 3,162
pediatric high grade glioma 1 | 2,712
primitive neuroectodermal tumor 1 | 3,031
progressive supranuclear palsy 1 | 674
psoriasis 1 | 6,685

Tissue

Blood and immune system 5 | 17,995
Cardiovascular System 5 | 17,958
Digestive Tract 5 | 18,473
Endocrine System 5 | 18,512
Female tissues 5 | 18,647
Liver and Pancreas 5 | 18,136
Male tissues 5 | 17,969
Nervous System 5 | 18,561
Respiratory system 5 | 17,484
Skin and soft tissues 5 | 18,115
Urinary Tract 5 | 18,444

Target Family

Enzyme 5 | 4,146

PathwayCommons: humancyc Pathway

tRNA splicing 5 | 5
superpathway of inositol phosp... 68 | 68
superpathway of conversion of ... 46 | 46
purine nucleotides de novo bio... 43 | 43
superpathway of purine nucleot... 43 | 43
tRNA charging 38 | 38
phospholipases 37 | 37
mucin core 1 and core 2 O-glyc... 28 | 28
3-phosphoinositide biosynthesi... 27 | 27
triacylglycerol biosynthesis 27 | 27
D-myo-inositol (1,4,5)-trispho... 25 | 25
superpathway of cholesterol bi... 25 | 25
gluconeogenesis 24 | 24
glycolysis 24 | 24
adenosine ribonucleotides de n... 23 | 23
CDP-diacylglycerol biosynthesi... 22 | 22
glutathione-mediated detoxific... 22 | 22
superpathway of pyrimidine deo... 21 | 21
3-phosphoinositide degradation 20 | 20
superpathway of D-myo-inositol... 20 | 20
D-myo-inositol-5-phosphate met... 19 | 19
retinol biosynthesis 18 | 18
TCA cycle 17 | 17
superpathway of methionine deg... 17 | 17
fatty acid β-oxidation 16 | 16
superpathway of pyrimidine deo... 16 | 16
the visual cycle I (vertebrate... 16 | 16
1D-myo-inositol hexakisphospha... 15 | 15
D-myo-inositol (1,3,4)-trispho... 15 | 15
fatty acid β-oxidation (p... 15 | 15
guanosine nucleotides de novo ... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
γ-linolenate biosynthesi... 14 | 14
bile acid biosynthesis, neutra... 14 | 14
superpathway of pyrimidine rib... 14 | 14
triacylglycerol degradation 14 | 14
D-myo-inositol (1,4,5)-trispho... 13 | 13
L-kynurenine degradation 13 | 13
cholesterol biosynthesis I 13 | 13
cholesterol biosynthesis II (v... 13 | 13
cholesterol biosynthesis III (... 13 | 13
icosapentaenoate biosynthesis ... 13 | 13
stearate biosynthesis 13 | 13
valine degradation 13 | 13
NAD de novo biosynthesis 12 | 12
UTP and CTP de novo biosynthes... 12 | 12
guanosine ribonucleotides de n... 12 | 12
isoleucine degradation 12 | 12
leucine degradation 12 | 12
purine deoxyribonucleosides sa... 12 | 12
superpathway of geranylgeranyl... 12 | 12
adenosine deoxyribonucleotides... 11 | 11
guanosine deoxyribonucleotides... 11 | 11
pyrimidine deoxyribonucleotide... 11 | 11
reactive oxygen species degrad... 11 | 11
CMP phosphorylation 10 | 10
mevalonate pathway 10 | 10
noradrenaline and adrenaline d... 10 | 10
purine nucleotides degradation 10 | 10
putrescine degradation III 10 | 10
terminal O-glycans residues mo... 10 | 10
C20 prostanoid biosynthesis 9 | 9
UDP-N-acetyl-D-galactosamine b... 9 | 9
dolichyl-diphosphooligosacchar... 9 | 9
glycogenolysis 9 | 9
heme biosynthesis 9 | 9
methionine salvage cycle III 9 | 9
serotonin degradation 9 | 9
sphingosine and sphingosine-1-... 9 | 9
tryptophan degradation 9 | 9
2-oxobutanoate degradation 8 | 8
chondroitin sulfate biosynthes... 8 | 8
fatty acid activation 8 | 8
retinoate biosynthesis I 8 | 8
sphingomyelin metabolism/ceram... 8 | 8
sucrose degradation 8 | 8
γ-glutamyl cycle 7 | 7
GABA shunt 7 | 7
adenosine nucleotides degradat... 7 | 7
androgen biosynthesis 7 | 7
ceramide de novo biosynthesis 7 | 7
chondroitin sulfate degradatio... 7 | 7
inositol pyrophosphates biosyn... 7 | 7
leukotriene biosynthesis 7 | 7
oxidative ethanol degradation ... 7 | 7
pentose phosphate pathway 7 | 7
serine and glycine biosynthesi... 7 | 7
superpathway of choline degrad... 7 | 7
thyroid hormone metabolism II ... 7 | 7
tryptophan degradation to 2-am... 7 | 7
ubiquinol-10 biosynthesis 7 | 7
2'-deoxy-α-D-ribose 1-ph... 6 | 6
GDP-mannose biosynthesis 6 | 6
cysteine biosynthesis 6 | 6
lysine degradation II (pipecol... 6 | 6
oleate biosynthesis 6 | 6
phosphatidylcholine biosynthes... 6 | 6
phosphatidylethanolamine biosy... 6 | 6
selenocysteine biosynthesis 6 | 6
zymosterol biosynthesis 6 | 6

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
tRNA-splicing endonuclease subunit Sen2 TSEN2 Tbio Enzyme -1.00789 10.1 118
tRNA-splicing endonuclease subunit Sen15 TSEN15 Tdark Enzyme -0.05782 2.16 47
tRNA-splicing endonuclease subunit Sen34 TSEN34 Tdark Enzyme -0.71461 5.01 17
tRNA-splicing endonuclease subunit Sen54 TSEN54 Tbio Enzyme -1.35507 22.2 30
tRNA 2'-phosphotransferase 1 TRPT1 Tdark Enzyme -0.16386 1.43 16