Development Level

Tbio 16 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Phenotype

increased body weight 2 | 42
abnormal gait 1 | 51
decreased body length 1 | 108
decreased body weight 1 | 174
decreased lean body mass 1 | 195
increased CD4-positive, CD25-p... 1 | 18
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
tremors 1 | 34

Disease

ovarian cancer 12 | 8,491
osteosarcoma 11 | 7,933
lung cancer 10 | 4,473
medulloblastoma, large-cell 10 | 6,234
glioblastoma 9 | 5,572
atypical teratoid / rhabdoid tumor 8 | 4,369
Oculocerebrorenal syndrome 7 | 24
Pick disease 7 | 1,893
lung carcinoma 7 | 2,844
adult high grade glioma 6 | 2,148
astrocytoma 6 | 1,493
lung adenocarcinoma 6 | 2,714
oligodendroglioma 6 | 2,849
pilocytic astrocytoma 6 | 3,086
psoriasis 6 | 6,685
Breast cancer 5 | 3,098
primitive neuroectodermal tumor 5 | 3,031
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
IGA Glomerulonephritis 4 | 454
colon cancer 4 | 1,475
malignant mesothelioma 4 | 3,163
pituitary cancer 4 | 1,972
Bipolar Disorder 3 | 266
Carcinoma 3 | 2,147
active Crohn's disease 3 | 918
cutaneous lupus erythematosus 3 | 1,056
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
invasive ductal carcinoma 3 | 2,950
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
pediatric high grade glioma 3 | 2,712
posterior fossa group B ependymoma 3 | 1,530
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Autistic Disorder 2 | 320
Bannayan-Riley-Ruvalcaba syndrome 2 | 8
Dent disease 2 | 20
Dermatologic disorders 2 | 65
Down syndrome 2 | 548
Endometriosis 2 | 535
Intellectual disability 2 | 573
Juvenile polyposis syndrome 2 | 7
Mammary Neoplasms 2 | 410
Multiple myeloma 2 | 1,327
Parkinson's disease 2 | 364
Reperfusion Injury 2 | 84
Schizophrenia 2 | 503
Thyroid Cancer, Nonmedullary, 2 2 | 6
Thyroid cancer, follicular 2 | 7
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
esophageal adenocarcinoma 2 | 737
glioblastoma multiforme 2 | 347
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 788
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686
Adenocarcinoma 1 | 115
Anisometropia 1 | 16
Arsenic Poisoning 1 | 59
Brachydactyly 1 | 52
CMM1 1 | 5
Catel Manzke syndrome 1 | 2
Chondrodysplasia with joint dislocations, GPAPP type 1 | 1
Ciliopathy 1 | 57
Cleft palate 1 | 125
Craniofacial Abnormalities 1 | 147
DOID:2627 1 | 14
Desbuquois dysplasia 1 | 9
Developmental Disabilities 1 | 20
Dystonia 1 | 77
Glioma 1 | 66
Head and neck squamous cell carcinoma 1 | 12
Kidney cancer 1 | 121
Language Development Disorders 1 | 9
Lipoma 1 | 19
Long QT syndrome 1 | 53
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 4
Melanoma 1 | 261
Motor Skills Disorders 1 | 6
Neoplasm Invasiveness 1 | 127
Neoplastic Syndromes, Hereditary 1 | 48
Osteoarthritis 1 | 96
Parkinson Disease 1 | 105
Renal Cell Carcinoma 1 | 199
Rickets 1 | 42
Skin cancer 1 | 37
ovarian neoplasm 1 | 97

Tissue

Blood and immune system 20 | 17,994
Cardiovascular System 20 | 17,957
Digestive Tract 20 | 18,472
Endocrine System 20 | 18,511
Female tissues 20 | 18,646
Liver and Pancreas 20 | 18,135
Male tissues 20 | 17,968
Nervous System 20 | 18,560
Respiratory system 20 | 17,483
Skin and soft tissues 20 | 18,114
Urinary Tract 20 | 18,443

Target Family

Enzyme 14 | 4,146
Kinase 4 | 634
Non-IDG 2 | 11,969

PathwayCommons: humancyc Pathway

superpathway of D-myo-inositol... 20 | 20
superpathway of inositol phosp... 68 | 68
superpathway of conversion of ... 46 | 46
purine nucleotides de novo bio... 43 | 43
superpathway of purine nucleot... 43 | 43
tRNA charging 38 | 38
phospholipases 37 | 37
mucin core 1 and core 2 O-glyc... 28 | 28
3-phosphoinositide biosynthesi... 27 | 27
triacylglycerol biosynthesis 27 | 27
D-myo-inositol (1,4,5)-trispho... 25 | 25
superpathway of cholesterol bi... 25 | 25
gluconeogenesis 24 | 24
glycolysis 24 | 24
adenosine ribonucleotides de n... 23 | 23
CDP-diacylglycerol biosynthesi... 22 | 22
glutathione-mediated detoxific... 22 | 22
superpathway of pyrimidine deo... 21 | 21
3-phosphoinositide degradation 20 | 20
D-myo-inositol-5-phosphate met... 19 | 19
retinol biosynthesis 18 | 18
TCA cycle 17 | 17
superpathway of methionine deg... 17 | 17
fatty acid β-oxidation 16 | 16
superpathway of pyrimidine deo... 16 | 16
the visual cycle I (vertebrate... 16 | 16
1D-myo-inositol hexakisphospha... 15 | 15
D-myo-inositol (1,3,4)-trispho... 15 | 15
fatty acid β-oxidation (p... 15 | 15
guanosine nucleotides de novo ... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
γ-linolenate biosynthesi... 14 | 14
bile acid biosynthesis, neutra... 14 | 14
superpathway of pyrimidine rib... 14 | 14
triacylglycerol degradation 14 | 14
D-myo-inositol (1,4,5)-trispho... 13 | 13
L-kynurenine degradation 13 | 13
cholesterol biosynthesis I 13 | 13
cholesterol biosynthesis II (v... 13 | 13
cholesterol biosynthesis III (... 13 | 13
icosapentaenoate biosynthesis ... 13 | 13
stearate biosynthesis 13 | 13
valine degradation 13 | 13
NAD de novo biosynthesis 12 | 12
UTP and CTP de novo biosynthes... 12 | 12
guanosine ribonucleotides de n... 12 | 12
isoleucine degradation 12 | 12
leucine degradation 12 | 12
purine deoxyribonucleosides sa... 12 | 12
superpathway of geranylgeranyl... 12 | 12
adenosine deoxyribonucleotides... 11 | 11
guanosine deoxyribonucleotides... 11 | 11
pyrimidine deoxyribonucleotide... 11 | 11
reactive oxygen species degrad... 11 | 11
CMP phosphorylation 10 | 10
mevalonate pathway 10 | 10
noradrenaline and adrenaline d... 10 | 10
purine nucleotides degradation 10 | 10
putrescine degradation III 10 | 10
terminal O-glycans residues mo... 10 | 10
C20 prostanoid biosynthesis 9 | 9
UDP-N-acetyl-D-galactosamine b... 9 | 9
dolichyl-diphosphooligosacchar... 9 | 9
glycogenolysis 9 | 9
heme biosynthesis 9 | 9
methionine salvage cycle III 9 | 9
serotonin degradation 9 | 9
sphingosine and sphingosine-1-... 9 | 9
tryptophan degradation 9 | 9
2-oxobutanoate degradation 8 | 8
chondroitin sulfate biosynthes... 8 | 8
fatty acid activation 8 | 8
retinoate biosynthesis I 8 | 8
sphingomyelin metabolism/ceram... 8 | 8
sucrose degradation 8 | 8
γ-glutamyl cycle 7 | 7
GABA shunt 7 | 7
adenosine nucleotides degradat... 7 | 7
androgen biosynthesis 7 | 7
ceramide de novo biosynthesis 7 | 7
chondroitin sulfate degradatio... 7 | 7
inositol pyrophosphates biosyn... 7 | 7
leukotriene biosynthesis 7 | 7
oxidative ethanol degradation ... 7 | 7
pentose phosphate pathway 7 | 7
serine and glycine biosynthesi... 7 | 7
superpathway of choline degrad... 7 | 7
thyroid hormone metabolism II ... 7 | 7
tryptophan degradation to 2-am... 7 | 7
ubiquinol-10 biosynthesis 7 | 7
2'-deoxy-α-D-ribose 1-ph... 6 | 6
GDP-mannose biosynthesis 6 | 6
cysteine biosynthesis 6 | 6
lysine degradation II (pipecol... 6 | 6
oleate biosynthesis 6 | 6
phosphatidylcholine biosynthes... 6 | 6
phosphatidylethanolamine biosy... 6 | 6
selenocysteine biosynthesis 6 | 6
zymosterol biosynthesis 6 | 6

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.84616 8.89 74
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.74048 58.0 91
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.17795 160.1 198
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.82701 66.8 118
Inositol monophosphatase 1 IMPA1 Tclin Enzyme -2.31308 195.7 73
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tchem Enzyme -3.66888 4696.1 874
Inositol-trisphosphate 3-kinase A ITPKA Tbio Kinase -1.40145 25.8 139
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.01782 134.9 212
Inositol monophosphatase 2 IMPA2 Tbio Enzyme -1.48299 31.4 60
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 INPP5D Tbio Enzyme -2.02617 96.0 328