Development Level

Tbio 4 | 10,625
Tchem 3 | 1,890
Tclin 3 | 602

IMPC Term

decreased bone mineral density 2 | 126
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal response to tactile s... 1 | 16
abnormal startle reflex 1 | 14
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 7 | 8,484
psoriasis 7 | 6,685
lung cancer 6 | 4,466
non-small cell lung cancer 6 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
invasive ductal carcinoma 5 | 2,950
Alcohol dependence 4 | 107
acute myeloid leukemia 4 | 780
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
medulloblastoma, large-cell 4 | 6,234
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
Cancer 3 | 2,346
Succinic semialdehyde dehydrogenase deficiency 3 | 16
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
esophageal adenocarcinoma 3 | 737
glioblastoma 3 | 5,572
malignant mesothelioma 3 | 3,162
osteosarcoma 3 | 7,933
Alzheimer's disease 2 | 644
Attention deficit hyperactivity disorder 2 | 156
Autistic Disorder 2 | 320
Breast cancer 2 | 3,094
Colonic Neoplasms 2 | 126
Dementia 2 | 129
Depressive disorder 2 | 48
Endometriosis 2 | 535
Hepatic encephalopathy 2 | 25
Heroin dependence 2 | 30
Huntington Disease 2 | 12
Hypertensive disorder 2 | 58
Hypotension 2 | 53
Intellectual disability 2 | 573
Liver Cirrhosis, Experimental 2 | 108
Major Depressive Disorder 2 | 106
Parkinson Disease 2 | 102
Parkinson's disease 2 | 364
Pheochromocytoma 2 | 22
Schizophrenia 2 | 501
Substance abuse 2 | 55
Toxic encephalopathy 2 | 131
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
atypical teratoid / rhabdoid tumor 2 | 4,369
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung carcinoma 2 | 2,844
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
sonic hedgehog group medulloblastoma 2 | 1,482
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Alcoholic Intoxication, Chronic 1 | 41
Alopecia 1 | 55
Amyotrophic lateral sclerosis type 3 1 | 15
Antisocial personality disorder 1 | 9
Bipolar Disorder 1 | 266
Brain disease 1 | 83
Brain infarction 1 | 17
Cerebral palsy 1 | 28
Cerebrovascular accident 1 | 44
Chronic Lymphocytic Leukemia 1 | 242
Colorectal Neoplasms 1 | 217
Corneal dystrophy 1 | 15
Coronary artery disease 1 | 240
Coronary heart disease 1 | 59
Cyclothymic disorder 1 | 9
Esophageal Neoplasms 1 | 67
Exhibitionism 1 | 7
Gaucher disease type 1 1 | 171
Intracranial aneurysm 1 | 20
Kidney disease 1 | 396
Liver disease 1 | 219
Malignant neoplasm of esophagus 1 | 18
Melancholia 1 | 12
Myopathy 1 | 128
Quadriplegia 1 | 14
Refsum disease 1 | 21
Sengers syndrome 1 | 17
Squamous cell carcinoma of esophagus 1 | 82
Sudden infant death syndrome 1 | 33
Tinea capitis 1 | 12
Vascular Diseases 1 | 16
X-linked cerebral adrenoleukodystrophy 1 | 115
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis and chronic rhinosinusitis 1 | 213
facioscapulohumeral dystrophy 1 | 286
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer 1 | 270
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
interstitial lung disease 1 | 291
limb girdle muscular dystrophy 2B 1 | 74
non-inflammatory breast cancer 1 | 208
substance-related disorder 1 | 105

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Enzyme 10 | 4,146

PathwayCommons: humancyc Pathway

putrescine degradation III 10 | 10
superpathway of inositol phosp... 68 | 68
superpathway of conversion of ... 46 | 46
purine nucleotides de novo bio... 43 | 43
superpathway of purine nucleot... 43 | 43
tRNA charging 38 | 38
phospholipases 37 | 37
mucin core 1 and core 2 O-glyc... 28 | 28
3-phosphoinositide biosynthesi... 27 | 27
triacylglycerol biosynthesis 27 | 27
D-myo-inositol (1,4,5)-trispho... 25 | 25
superpathway of cholesterol bi... 25 | 25
gluconeogenesis 24 | 24
glycolysis 24 | 24
adenosine ribonucleotides de n... 23 | 23
CDP-diacylglycerol biosynthesi... 22 | 22
glutathione-mediated detoxific... 22 | 22
superpathway of pyrimidine deo... 21 | 21
3-phosphoinositide degradation 20 | 20
superpathway of D-myo-inositol... 20 | 20
D-myo-inositol-5-phosphate met... 19 | 19
retinol biosynthesis 18 | 18
TCA cycle 17 | 17
superpathway of methionine deg... 17 | 17
fatty acid β-oxidation 16 | 16
superpathway of pyrimidine deo... 16 | 16
the visual cycle I (vertebrate... 16 | 16
1D-myo-inositol hexakisphospha... 15 | 15
D-myo-inositol (1,3,4)-trispho... 15 | 15
fatty acid β-oxidation (p... 15 | 15
guanosine nucleotides de novo ... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
pyrimidine deoxyribonucleotide... 15 | 15
γ-linolenate biosynthesi... 14 | 14
bile acid biosynthesis, neutra... 14 | 14
superpathway of pyrimidine rib... 14 | 14
triacylglycerol degradation 14 | 14
D-myo-inositol (1,4,5)-trispho... 13 | 13
L-kynurenine degradation 13 | 13
cholesterol biosynthesis I 13 | 13
cholesterol biosynthesis II (v... 13 | 13
cholesterol biosynthesis III (... 13 | 13
icosapentaenoate biosynthesis ... 13 | 13
stearate biosynthesis 13 | 13
valine degradation 13 | 13
NAD de novo biosynthesis 12 | 12
UTP and CTP de novo biosynthes... 12 | 12
guanosine ribonucleotides de n... 12 | 12
isoleucine degradation 12 | 12
leucine degradation 12 | 12
purine deoxyribonucleosides sa... 12 | 12
superpathway of geranylgeranyl... 12 | 12
adenosine deoxyribonucleotides... 11 | 11
guanosine deoxyribonucleotides... 11 | 11
pyrimidine deoxyribonucleotide... 11 | 11
reactive oxygen species degrad... 11 | 11
CMP phosphorylation 10 | 10
mevalonate pathway 10 | 10
noradrenaline and adrenaline d... 10 | 10
purine nucleotides degradation 10 | 10
terminal O-glycans residues mo... 10 | 10
C20 prostanoid biosynthesis 9 | 9
UDP-N-acetyl-D-galactosamine b... 9 | 9
dolichyl-diphosphooligosacchar... 9 | 9
glycogenolysis 9 | 9
heme biosynthesis 9 | 9
methionine salvage cycle III 9 | 9
serotonin degradation 9 | 9
sphingosine and sphingosine-1-... 9 | 9
tryptophan degradation 9 | 9
2-oxobutanoate degradation 8 | 8
chondroitin sulfate biosynthes... 8 | 8
fatty acid activation 8 | 8
retinoate biosynthesis I 8 | 8
sphingomyelin metabolism/ceram... 8 | 8
sucrose degradation 8 | 8
γ-glutamyl cycle 7 | 7
GABA shunt 7 | 7
adenosine nucleotides degradat... 7 | 7
androgen biosynthesis 7 | 7
ceramide de novo biosynthesis 7 | 7
chondroitin sulfate degradatio... 7 | 7
inositol pyrophosphates biosyn... 7 | 7
leukotriene biosynthesis 7 | 7
oxidative ethanol degradation ... 7 | 7
pentose phosphate pathway 7 | 7
serine and glycine biosynthesi... 7 | 7
superpathway of choline degrad... 7 | 7
thyroid hormone metabolism II ... 7 | 7
tryptophan degradation to 2-am... 7 | 7
ubiquinol-10 biosynthesis 7 | 7
2'-deoxy-α-D-ribose 1-ph... 6 | 6
GDP-mannose biosynthesis 6 | 6
cysteine biosynthesis 6 | 6
lysine degradation II (pipecol... 6 | 6
oleate biosynthesis 6 | 6
phosphatidylcholine biosynthes... 6 | 6
phosphatidylethanolamine biosy... 6 | 6
selenocysteine biosynthesis 6 | 6
zymosterol biosynthesis 6 | 6

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.26785 189.3 264
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.37979 2431.7 224
Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 Tchem Enzyme -2.10131 137.8 276
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.69341 49.3 173
Aldehyde dehydrogenase family 3 member B2 ALDH3B2 Tchem Enzyme -0.88158 6.77 143
Diamine acetyltransferase 2 SAT2 Tchem Enzyme -0.91777 9.01 43
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.36609 2411.2 259
Diamine acetyltransferase 1 SAT1 Tbio Enzyme -2.57122 395.2 150
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.94090 942.0 411
Aldehyde dehydrogenase family 3 member B1 ALDH3B1 Tbio Enzyme 0.00000 152