Development Level

Tbio 3 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Carcinoma 6 | 11,493
medulloblastoma, large-cell 5 | 6,241
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
psoriasis 4 | 6,694
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
Alcohol abuse 2 | 50
Alcohol dependence 2 | 107
Alcohol-Related Disorders 2 | 5
Alcoholic Intoxication, Chronic 2 | 289
Alcoholism 2 | 45
Atopic dermatitis 2 | 952
Cancer 2 | 2,499
Flushing 2 | 60
Liver disease 2 | 237
Substance abuse 2 | 59
Succinic semialdehyde dehydrogenase deficiency 2 | 16
adrenocortical carcinoma 2 | 1,428
ependymoma 2 | 4,679
fibroadenoma 2 | 559
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Abnormal skeletal development 1 | 60
Abnormality of retinal pigmentation 1 | 111
Adenocarcinoma 1 | 122
Adverse reaction to drug 1 | 61
Alcoholic Intoxication 1 | 34
Brain infarction 1 | 22
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiomegaly 1 | 116
Central nervous system demyelination 1 | 28
Cerebral palsy 1 | 40
Chemical and Drug Induced Liver Injury 1 | 195
Colorectal Neoplasms 1 | 243
Corneal erosion 1 | 16
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Drug Eruptions 1 | 18
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dry skin 1 | 75
Dysarthria 1 | 192
Dysplasia of tooth enamel 1 | 35
Erythema 1 | 58
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Gaucher disease type 1 1 | 180
Heart Injuries 1 | 3
Heroin dependence 1 | 30
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Intracranial aneurysm 1 | 24
Kyphosis deformity of spine 1 | 114
Liver Cirrhosis, Experimental 1 | 769
Liver Neoplasms, Experimental 1 | 59
Lung Neoplasms 1 | 232
Lymphoma, Non-Hodgkin 1 | 24
Macular degeneration 1 | 65
Muscle Spasticity 1 | 195
Myopia 1 | 176
Necrosis 1 | 53
Neoplasm Invasiveness 1 | 161
Non-alcoholic Fatty Liver Disease 1 | 42
Osteochondrodysplasias 1 | 72
Parkinson Disease 1 | 64
Photodysphoria 1 | 121
Photophobia 1 | 121
Precancerous Conditions 1 | 80
Pyramidal sign 1 | 29
Quadriplegia 1 | 20
Retinal Diseases 1 | 55
Retinal pigment epithelial abnormality 1 | 111
Sengers syndrome 1 | 18
Squamous cell carcinoma of esophagus 1 | 77
Thin dental enamel 1 | 35
Vascular Diseases 1 | 16
Wernicke-Korsakoff syndrome 1 | 10
X-linked cerebral adrenoleukodystrophy 1 | 116
Xerosis 1 | 75
esophageal cancer 1 | 22
facioscapulohumeral dystrophy 1 | 288
limb girdle muscular dystrophy 2B 1 | 40
non-small cell lung carcinoma 1 | 317
posterior fossa group B ependymoma 1 | 416

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 2 | 12,091

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 Tbio Enzyme -1.48800 26.8 73
Putative inactive cytochrome P450 2G1 CYP2G1P Tdark Non-IDG 0.00000 0
Acyl-CoA synthetase short-chain family member 3, mitochondrial ACSS3 Tdark Enzyme -0.54149 2.91 84
Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 Tbio Enzyme -2.25828 174.5 264
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Cytochrome P450 2E1 CYP2E1 Tchem Non-IDG -3.41434 2667.8 411