Development Level

Tbio 7 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal sensory capabilities-... 1 | 8
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
ductal carcinoma in situ 5 | 1,745
invasive ductal carcinoma 5 | 2,951
osteosarcoma 5 | 7,950
Pellagra 4 | 26
glioblastoma 4 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Major Depressive Disorder 3 | 301
Unipolar Depression 3 | 250
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
primary Sjogren syndrome 3 | 735
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Abnormality of the musculature 1 | 16
Age related macular degeneration 1 | 72
Agoraphobia 1 | 21
Aminoaciduria 1 | 38
Amyotrophic lateral sclerosis 1 | 451
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Bipolar Disorder 1 | 666
Blindness 1 | 88
Comatose 1 | 56
Congenital deafness 1 | 185
Deafness 1 | 198
Depressed mood 1 | 17
Dermatitis, Allergic Contact 1 | 67
Down syndrome 1 | 499
Elevated heart rate 1 | 25
Fundus dystrophy 1 | 83
Gilles de la Tourette syndrome 1 | 47
Hearing Loss, Partial 1 | 185
Huntington's disease 1 | 76
Hypotension 1 | 82
Inflammation 1 | 120
Leber congenital amaurosis 1 | 69
Macular degeneration 1 | 65
Metabolic acidosis 1 | 90
Multiple Sclerosis 1 | 540
Muscle Hypertonia 1 | 88
Narcolepsy 1 | 72
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Nonorganic psychosis 1 | 84
Polycystic ovary syndrome 1 | 360
Psychotic Disorders 1 | 151
Rectal prolapse 1 | 19
Retinal Degeneration 1 | 106
Rickets 1 | 49
Systemic lupus erythematosus 1 | 194
Tachycardia 1 | 43
Type 2 diabetes mellitus 1 | 272
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
chronic rhinosinusitis 1 | 512
fibroadenoma 1 | 559
gastric carcinoma 1 | 807
hearing impairment 1 | 199
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
nutritional deficiency disease 1 | 9
pediatric high grade glioma 1 | 1,064
periodontitis 1 | 293
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primary pancreatic ductal adenocarcinoma 1 | 1,109
spina bifida 1 | 1,074
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Enzyme 10 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamine-dependent NAD(+) synthetase NADSYN1 Tbio Enzyme -1.21917 15.2 60
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.54038 36.0 111
Kynureninase KYNU Tchem Enzyme -1.61116 39.2 173
Kynurenine formamidase AFMID Tbio Enzyme -1.65562 44.8 67
3-hydroxyanthranilate 3,4-dioxygenase HAAO Tbio Enzyme -1.76359 56.1 114
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 NMNAT3 Tbio Enzyme -1.31765 20.1 141
Kynurenine 3-monooxygenase KMO Tchem Enzyme -2.15501 134.1 127
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 NMNAT1 Tbio Enzyme -1.90480 77.3 145
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193
Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT Tbio Enzyme -2.02559 104.4 189