Development Level

Tbio 12 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal facial morphology 1 | 17
abnormal placenta morphology 1 | 5
abnormal retinal vasculature m... 1 | 27
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
prenatal lethality 1 | 28
unresponsive to tactile stimul... 1 | 8

Disease

medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
pediatric high grade glioma 6 | 1,064
Carcinoma 5 | 11,493
ependymoma 5 | 4,679
primitive neuroectodermal tumor 5 | 3,035
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Pick disease 3 | 1,894
astrocytoma 3 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acute Erythroblastic Leukemia 2 | 3
Anemia 2 | 365
Anemia, Hypoplastic, Congenital 2 | 2
Anemia, Sickle Cell 2 | 8
Astrocytoma, Pilocytic 2 | 3,081
Beta thalassemia 2 | 16
Carcinoma, Hepatocellular 2 | 228
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Congenital hypoplastic anemia 2 | 8
Global developmental delay 2 | 608
Hemoglobin low 2 | 124
Hereditary spherocytosis 2 | 16
Leukemia, Erythroblastic, Acute 2 | 3
Liver carcinoma 2 | 240
Mental and motor retardation 2 | 608
Pain disorder 2 | 15
Spherocytosis, Hereditary 2 | 5
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
beta-Thalassemia 2 | 10
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Abdominal Pain 1 | 98
Acanthocytosis 1 | 7
Bone pain 1 | 42
Breast Neoplasms 1 | 445
Broad-based gait 1 | 19
Colonic Neoplasms 1 | 142
Congenital disorder of glycosylation 1 | 54
Defective T cell proliferation 1 | 1
Desbuquois dysplasia 1 | 13
Diarrhea 1 | 253
Diastrophic dysplasia 1 | 21
Downward slant of palpebral fissure 1 | 158
Fever 1 | 138
Gastrointestinal Stromal Tumors 1 | 48
Hip Dislocation, Congenital 1 | 48
Hyperammonemia 1 | 30
Hypertrophic Cardiomyopathy 1 | 117
Hypoxia 1 | 33
IMMUNODEFICIENCY 24 1 | 1
Immunoglobulin IgG2 deficiency 1 | 3
Immunologic Deficiency Syndromes 1 | 113
Infantile onset 1 | 238
Isolated cases 1 | 72
Lymphopenia 1 | 67
Mammary Neoplasms 1 | 425
Mouth Neoplasms 1 | 55
Myoclonus 1 | 74
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Opsoclonus 1 | 5
Orotic aciduria 1 | 18
Primary ciliary dyskinesia 1 | 76
Recurrent respiratory infections 1 | 141
Renal tubular acidosis 1 | 24
Reticular dysgenesis 1 | 7
Situs Inversus 1 | 65
Situs ambiguus 1 | 25
Squamous cell carcinoma 1 | 129
Substance-Related Disorders 1 | 115
Thrombophlebitis 1 | 19
Weight decreased 1 | 103
non-small cell lung carcinoma 1 | 317
permanent atrial fibrillation 1 | 45

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Kinase 9 | 634
Enzyme 5 | 4,145
Non-IDG 1 | 12,091

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CAD protein CAD Tchem Non-IDG -2.23887 168.4 224
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Nucleoside diphosphate kinase B NME1-NME2 Tbio Kinase -2.85003 1033.0 85
UMP-CMP kinase 2, mitochondrial CMPK2 Tbio Kinase -1.60739 42.5 79
Nucleoside diphosphate kinase homolog 5 NME5 Tbio Kinase -0.86091 6.37 122
Nucleoside diphosphate kinase, mitochondrial NME4 Tbio Kinase -1.75871 56.4 240
Putative nucleoside diphosphate kinase NME2P1 Tdark Kinase -2.85003 1033.0 0
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42839 27.2 210