Development Level

Tbio 12 | 11,445
Tchem 12 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 5 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

embryonic lethality prior to o... 4 | 239
preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
embryonic growth retardation 2 | 106
abnormal epididymis morphology 1 | 42
abnormal testis morphology 1 | 43
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased grip strength 1 | 116
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 24 | 11,493
osteosarcoma 17 | 7,950
ovarian cancer 17 | 8,520
medulloblastoma, large-cell 11 | 6,241
Kidney cancer 10 | 2,613
glioblastoma 10 | 5,792
lung cancer 9 | 4,740
atypical teratoid / rhabdoid tumor 8 | 5,112
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
Cancer 7 | 2,499
Schizophrenia 7 | 1,160
ependymoma 7 | 4,679
adult high grade glioma 6 | 3,801
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Autosomal recessive predisposition 5 | 1,442
Waldenstrons macroglobulinemia 5 | 765
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
juvenile dermatomyositis 5 | 1,187
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
DOID:2627 4 | 94
Diffuse large B-cell lymphoma 4 | 39
Hypoplastic mandible condyle 4 | 275
Lymphoma, Large B-Cell, Diffuse 4 | 34
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
follicular lymphoma 4 | 20
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
Cataract 3 | 297
Centronuclear myopathy 3 | 27
Endometrial cancer 3 | 311
Fatigue 3 | 182
Frontal bossing 3 | 157
Lens Opacities 3 | 231
Liver cancer 3 | 604
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Orbital separation excessive 3 | 244
Polymicrogyria 3 | 48
Skeletal muscle atrophy 3 | 139
Ventricular Septal Defects 3 | 119
Yunis-Varon syndrome 3 | 6
astrocytic glioma 3 | 2,597
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
muscle degeneration 3 | 139
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Amyotrophic lateral sclerosis 2 | 451
Arthrogryposis 2 | 54
Bipolar Disorder 2 | 666
Concave bridge of nose 2 | 195
Decreased tendon reflex 2 | 122
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Diarrhea 2 | 253
Dilated ventricles (finding) 2 | 121
Epilepsy 2 | 792
Failure to gain weight 2 | 365
High forehead 2 | 102
Hypothyroidism 2 | 122
Long narrow head 2 | 75
Microstomia 2 | 78
Myopia 2 | 176
Neurodegenerative disease 2 | 414
Pachygyria 2 | 41
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Progressive disorder 2 | 142
Reflex, Deep Tendon, Absent 2 | 92
Seizures 2 | 596
Syndactyly of the toes 2 | 45
Tall forehead 2 | 102
Telecanthus 2 | 62
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Kinase 18 | 634
Enzyme 9 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 68 | 68
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