Development Level

Tbio 6 | 11,445
Tclin 4 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123

Disease

psoriasis 8 | 6,694
Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
Alcohol abuse 3 | 50
Attention deficit hyperactivity disorder 3 | 278
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Substance abuse 3 | 59
Succinic semialdehyde dehydrogenase deficiency 3 | 16
esophageal adenocarcinoma 3 | 737
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
primitive neuroectodermal tumor 3 | 3,035
substance-related disorder 3 | 162
ulcerative colitis 3 | 1,819
Alcoholic Intoxication 2 | 34
Alcoholism 2 | 45
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Chromosome Aberrations 2 | 16
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Dementia 2 | 175
Depressive disorder 2 | 409
Endometriosis 2 | 540
Esophageal Neoplasms 2 | 69
Esophageal Squamous Cell Carcinoma 2 | 77
Flushing 2 | 60
Genetic Predisposition to Disease 2 | 27
Hangover from alcohol 2 | 2
Hepatic encephalopathy 2 | 27
Heroin dependence 2 | 30
Huntington Disease 2 | 13
Hypertensive disorder 2 | 56
Hypotension 2 | 82
Intellectual disability 2 | 1,016
Liver disease 2 | 237
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Mood Disorders 2 | 184
Norrie disease 2 | 14
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Pheochromocytoma 2 | 24
Plague 2 | 19
Psychotic Disorders 2 | 151
Schizophrenia 2 | 1,160
Squamous cell carcinoma of esophagus 2 | 77
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
Wernicke-Korsakoff syndrome 2 | 10
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 214
ependymoma 2 | 4,679
esophageal cancer 2 | 22
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
tuberculosis 2 | 2,010
Antisocial personality disorder 1 | 9
Atypical depressive disorder 1 | 6
Barrett's esophagus 1 | 182
Brain disease 1 | 96
Central nervous system demyelination 1 | 28
Dry skin 1 | 75
Erythema 1 | 58
Exhibitionism 1 | 7
Hyperkeratosis 1 | 50
Intracranial aneurysm 1 | 24
Macular degeneration 1 | 65
Melancholia 1 | 10
Photodysphoria 1 | 121
Sudden infant death syndrome 1 | 32
X- linked recessive 1 | 110
Xerosis 1 | 75
interstitial lung disease 1 | 298

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Liver and Pancreas 10 | 16,750
Urinary Tract 10 | 16,678
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Blood and immune system 8 | 16,909
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Enzyme 10 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.39309 2492.1 292
Sulfotransferase 1A1 SULT1A1 Tbio Enzyme -2.48197 334.8 278
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Alcohol dehydrogenase 1B ADH1B Tclin Enzyme -2.42307 381.5 160
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
UDP-glucuronosyltransferase 2B10 UGT2B10 Tbio Enzyme -1.28053 19.5 91
Sulfotransferase 1A2 SULT1A2 Tbio Enzyme -1.83327 67.4 60
UDP-glucuronosyltransferase 2B11 UGT2B11 Tbio Enzyme -0.26858 1.79 52