Development Level

Tbio 3 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
edema 1 | 59
increased circulating bilirubi... 1 | 16
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
thrombocytopenia 1 | 56

Disease

Autosomal recessive predisposition 3 | 1,442
Epilepsy 3 | 792
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Seizures 3 | 596
Serine deficiency 3 | 9
ependymoma 3 | 4,679
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Carcinoma, Non-Small-Cell Lung 2 | 107
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Global developmental delay 2 | 608
Hypoplastic mandible condyle 2 | 275
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mandibular hypoplasia 2 | 275
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microcephaly 2 | 166
Micrognathism 2 | 275
Muscle Hypertonia 2 | 88
Neu Laxova syndrome 2 | 2
Neu-Laxova syndrome 2 | 2
Neu-Laxova syndrome 1 2 | 2
Orbital separation excessive 2 | 244
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Reduced fetal movement 2 | 51
Short neck 2 | 140
Sloping forehead 2 | 46
Small head 2 | 374
Uranostaphyloschisis 2 | 167
Vertical Talus 2 | 25
colon cancer 2 | 1,478
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Acquired scoliosis 1 | 281
Adducted thumb 1 | 22
Adenocarcinoma of lung 1 | 142
Breast Neoplasms 1 | 445
Byzanthine arch palate 1 | 194
Cardiovascular system disease 1 | 246
Congenital Bilateral Cataracts 1 | 50
Congenital cataract 1 | 50
Contracture of joint of hand 1 | 30
Curvature of spine 1 | 282
Decreased platelet count 1 | 111
Disease Models, Animal 1 | 155
Exophthalmos 1 | 112
Foramen Ovale, Patent 1 | 10
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hypsarrhythmia 1 | 25
Ichthyoses 1 | 41
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Lissencephaly 1 | 69
Liver neoplasms 1 | 130
MYELODYSPLASTIC SYNDROME 1 | 53
Macrotia 1 | 87
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Polyhydramnios 1 | 108
Poor growth 1 | 114
Prenatal onset 1 | 139
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Short cord 1 | 5
Small placenta 1 | 4
Spastic Quadriplegia 1 | 42
Syndactyly of the toes 1 | 45
Thrombocytopenia 1 | 197
Very poor growth 1 | 114
X-linked cerebral adrenoleukodystrophy 1 | 116
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
atypical teratoid/rhabdoid tumor 1 | 357

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 3 | 3
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
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http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
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http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
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http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
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http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
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http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
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http://pathwaycommons.org/pc2/... 7 | 7
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http://pathwaycommons.org/pc2/... 7 | 7
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http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
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http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.17330 1408.2 293
Phosphoserine phosphatase PSPH Tbio Enzyme -1.56433 55.8 252
Phosphoserine aminotransferase PSAT1 Tbio Enzyme -2.25926 176.4 136