Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased body length 2 | 101
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
increased body weight 1 | 25
increased mean corpuscular vol... 1 | 92

Disease

ovarian cancer 9 | 8,520
osteosarcoma 7 | 7,950
Carcinoma 6 | 11,493
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
cystic fibrosis 5 | 1,696
glioblastoma 5 | 5,792
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Endometriosis 3 | 540
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Macular degeneration 2 | 65
Pseudoxanthoma elasticum 2 | 18
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
Abnormal skeletal development 1 | 60
Abnormal trabecular bone morphology 1 | 6
Abnormality of the cerebral vasculature 1 | 6
Age related macular degeneration 1 | 72
Agoraphobia 1 | 21
Anemia 1 | 365
Ankylosis 1 | 28
Arthropathy 1 | 43
Barrett's esophagus 1 | 182
Blindness 1 | 88
Bone pain 1 | 42
Calcinosis 1 | 70
Chondrocalcinosis 1 | 9
Chromosome 1q21.1 deletion syndrome 1 | 12
Congestive heart failure 1 | 113
Craniosynostosis 1 | 74
Dental abscess 1 | 4
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Ecchymosis 1 | 66
Enthesitis 1 | 3
Exanthema 1 | 43
Excess nuchal skin 1 | 30
Excessive wrinkled skin 1 | 16
Fundus dystrophy 1 | 83
Genu varum 1 | 29
Heart conduction disease 1 | 83
Heart failure 1 | 162
Hereditary macular coloboma 1 | 5
Hip joint varus deformity - observation 1 | 24
Hyperkeratosis 1 | 50
Hyperphosphaturia 1 | 21
Hypophosphatasia 1 | 10
Hypophosphatemia 1 | 40
Hypophosphatemic Rickets 1 | 11
Increased tendency to bruise 1 | 66
Late tooth eruption 1 | 61
Leber congenital amaurosis 1 | 69
Linear atrophy 1 | 15
Liver Cirrhosis, Experimental 1 | 769
Malabsorption 1 | 82
Myocardial Infarction 1 | 151
Myopia 1 | 176
Neurobehavioral Manifestations 1 | 9
Osteoarthritis 1 | 184
Osteochondrodysplasias 1 | 72
Osteomalacia 1 | 35
Osteosclerosis 1 | 31
Polyarthritis 1 | 11
Renal phosphate wasting 1 | 7
Retinal Degeneration 1 | 106
Retinal Diseases 1 | 55
Retinal Hemorrhage 1 | 6
Rickets 1 | 49
Sensorineural Hearing Loss (disorder) 1 | 284
Skull malformation 1 | 38
Spinal canal stenosis 1 | 12
Stomach Neoplasms 1 | 300
Systemic lupus erythematosus 1 | 194
Tibial bowing 1 | 19
Urine phosphorous concentration above normal 1 | 21
Urticaria 1 | 67
non-small cell lung carcinoma 1 | 317
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192
Nervous System 11 | 16,725

Target Family

Enzyme 10 | 4,145
Kinase 2 | 634

PathwayCommons: humancyc Pathway

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