Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal sensory capabilities-... 1 | 8
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 4 | 11,493
Major Depressive Disorder 3 | 301
Pellagra 3 | 26
Unipolar Depression 3 | 250
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Liver Cirrhosis, Experimental 2 | 769
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Abnormality of the musculature 1 | 16
Abnormality of the respiratory system 1 | 4
Aminoaciduria 1 | 38
Amyotrophic lateral sclerosis 1 | 451
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Autosomal recessive predisposition 1 | 1,442
Bipolar Disorder 1 | 666
Cognitive delay 1 | 608
Comatose 1 | 56
Congenital deafness 1 | 185
Deafness 1 | 198
Depressed mood 1 | 17
Depression, Bipolar 1 | 12
Dermatitis, Allergic Contact 1 | 67
Dull intelligence 1 | 645
Elevated heart rate 1 | 25
Gilles de la Tourette syndrome 1 | 47
Global developmental delay 1 | 608
Hearing Loss, Partial 1 | 185
Huntington's disease 1 | 76
Hydroxykynureninuria 1 | 1
Hypotension 1 | 82
Inflammation 1 | 120
Intellectual disability 1 | 1,016
Iridocyclitis 1 | 19
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Metabolic acidosis 1 | 90
Multiple Sclerosis 1 | 540
Muscle Hypertonia 1 | 88
Narcolepsy 1 | 72
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Nonorganic psychosis 1 | 84
Nonprogressive encephalopathy 1 | 1
Photosensitivity disease 1 | 1
Poor school performance 1 | 645
Porphyria 1 | 10
Psychotic Disorders 1 | 151
Renal tubular disorder 1 | 12
SCHIZOPHRENIA 1 (disorder) 1 | 1
Starvation 1 | 1
Tachycardia 1 | 43
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
chronic rhinosinusitis 1 | 512
gastric carcinoma 1 | 807
hearing impairment 1 | 199
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
periodontitis 1 | 293
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primitive neuroectodermal tumor 1 | 3,035
spina bifida 1 | 1,074

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 5 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
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http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kynureninase KYNU Tchem Enzyme -1.61116 39.2 173
Kynurenine formamidase AFMID Tbio Enzyme -1.65562 44.8 67
3-hydroxyanthranilate 3,4-dioxygenase HAAO Tbio Enzyme -1.76359 56.1 114
Kynurenine 3-monooxygenase KMO Tchem Enzyme -2.15501 134.1 127
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193