Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal body wall morphology 1 | 9
abnormal embryo size 1 | 220
anophthalmia 1 | 33
increased body length 1 | 32
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Autosomal recessive predisposition 3 | 1,442
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
beta-ketothiolase deficiency 3 | 13
ovarian cancer 3 | 8,520
Cognitive delay 2 | 608
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
Pediatric failure to thrive 2 | 365
Vomiting 2 | 116
Waldenstrons macroglobulinemia 2 | 765
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
Abnormal amniotic fluid 1 | 6
Acetyl-Coa Acetyltransferase-2 Deficiency 1 | 1
Acidosis, Lactic 1 | 97
Amino acid metabolic disorder 1 | 5
Big calvaria 1 | 147
Breast Neoplasms 1 | 445
Bulging forehead 1 | 66
Cardiomyopathy 1 | 116
Cardiomyopathy, Hypertrophic, Familial 1 | 9
Carnitine palmitoyltransferase II deficiency 1 | 14
Chondrodysplasia punctata 1 | 41
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Congenital anomaly of face 1 | 56
Congestive heart failure 1 | 113
Corneal dystrophy 1 | 24
D-2-hydroxyglutaric aciduria 1 | 9
Dehydration 1 | 40
Delayed myelination 1 | 22
Dilation of lateral ventricles 1 | 4
Distortion of face 1 | 46
Dyskinetic syndrome 1 | 16
Dysmorphic facies 1 | 46
Dystonia 1 | 164
Dystonic disease 1 | 106
Elevated hepatic transaminases 1 | 81
Encephalopathies 1 | 43
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Fatty Liver 1 | 70
Funny looking face 1 | 46
Gaucher's disease 1 | 26
Generalized muscle weakness 1 | 57
Glutaric acidemia 1 | 4
Glutaric aciduria 1 | 5
Heart Diseases 1 | 43
Heart failure 1 | 162
Hepatic enzyme increased 1 | 81
Hydrops Fetalis 1 | 21
Hyperammonemia 1 | 30
Hypertrophic cardiomyopathy 20 1 | 12
Hypoketotic hypoglycemia 1 | 11
Hypoparathyroidism 1 | 41
Increased head circumference 1 | 147
Increased serum lactate 1 | 60
Increased serum pyruvate 1 | 9
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Irritation - emotion 1 | 68
Isolated cases 1 | 72
Ketonemia 1 | 11
Ketosis 1 | 11
Kidney Failure, Chronic 1 | 46
Lactic acidemia 1 | 95
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Little's Disease 1 | 14
Liver Cirrhosis, Experimental 1 | 769
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low Birth Weights 1 | 69
Mammary Neoplasms 1 | 425
Metabolic acidosis 1 | 90
Muscle Rigidity 1 | 49
Myalgia 1 | 54
Neuropathy 1 | 261
Opisthotonus 1 | 14
Organic acidemia 1 | 4
Peripheral Neuropathy 1 | 134
Prominent forehead 1 | 66
Respiratory Failure 1 | 104
Small for gestational age (disorder) 1 | 69
Subclinical abnormal liver function tests 1 | 81
Transaminases increased 1 | 81
Very long chain acyl-CoA dehydrogenase deficiency 1 | 10
Wide bregma sutures 1 | 46
Zellweger syndrome 1 | 37
alpha-methylacyl-CoA racemase deficiency 1 | 9
facial deformity 1 | 46

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 6 | 6
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http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetyl-CoA acetyltransferase, cytosolic ACAT2 Tbio Enzyme -1.75917 52.6 283
3-ketoacyl-CoA thiolase, peroxisomal ACAA1 Tbio Enzyme -2.31883 203.8 197
Acetyl-CoA acetyltransferase, mitochondrial ACAT1 Tchem Enzyme -1.85518 70.4 397
Glutaryl-CoA dehydrogenase, mitochondrial GCDH Tbio Enzyme -2.52555 327.8 181
Trifunctional enzyme subunit beta, mitochondrial HADHB Tbio Enzyme -2.05645 118.4 185