Development Level

Tbio 6 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

IMPC Phenotype

decreased bone mineral density 2 | 126
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Carcinoma 6 | 11,493
lung cancer 6 | 4,740
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Alcoholic Intoxication, Chronic 5 | 289
Schizophrenia 5 | 1,160
invasive ductal carcinoma 5 | 2,951
Alcohol dependence 4 | 107
Bipolar Disorder 4 | 666
acute myeloid leukemia 4 | 783
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Depressive disorder 3 | 409
Major Depressive Disorder 3 | 301
Mood Disorders 3 | 184
Succinic semialdehyde dehydrogenase deficiency 3 | 16
Unipolar Depression 3 | 250
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
malignant mesothelioma 3 | 3,232
osteosarcoma 3 | 7,950
Alcohol abuse 2 | 50
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Colonic Neoplasms 2 | 142
Dementia 2 | 175
Dry skin 2 | 75
Endometriosis 2 | 540
Flushing 2 | 60
Hepatic encephalopathy 2 | 27
Heroin dependence 2 | 30
Huntington Disease 2 | 13
Hypertensive disorder 2 | 56
Hypotension 2 | 82
Ichthyosis 2 | 56
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Mental Depression 2 | 333
Norrie disease 2 | 14
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Pheochromocytoma 2 | 24
Photodysphoria 2 | 121
Photophobia 2 | 121
Psychotic Disorders 2 | 151
Substance abuse 2 | 59
Toxic encephalopathy 2 | 141
X- linked recessive 2 | 110
Xerosis 2 | 75
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
Anemia, Megaloblastic 1 | 16
Antisocial personality disorder 1 | 9
Atypical depressive disorder 1 | 6
Cocaine Dependence 1 | 51
Conduct disorder 1 | 33
Corneal Injuries 1 | 1
Cyclothymic disorder 1 | 8
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Dysplasia of tooth enamel 1 | 35
Erythema 1 | 58
Exhibitionism 1 | 7
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Kyphosis deformity of spine 1 | 114
Macular degeneration 1 | 65
Nonorganic psychosis 1 | 84
Palmoplantar keratosis 1 | 74
Plaque, Amyloid 1 | 2
Precancerous Conditions 1 | 80
Scarring alopecia of scalp 1 | 13
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sudden infant death syndrome 1 | 32
Thin dental enamel 1 | 35

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Enzyme 10 | 4,145

PathwayCommons: humancyc Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Diamine acetyltransferase 1 SAT1 Tbio Enzyme -2.60045 409.5 159
Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 Tchem Enzyme -2.12624 141.3 310
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.73034 52.5 194
Aldehyde dehydrogenase family 3 member B2 ALDH3B2 Tbio Enzyme -0.92036 7.80 176
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Diamine acetyltransferase 2 SAT2 Tbio Enzyme -1.02462 10.2 55
Amine oxidase [flavin-containing] A MAOA Tclin Enzyme -3.39309 2492.1 292
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Aldehyde dehydrogenase family 3 member B1 ALDH3B1 Tbio Enzyme 0.00000 182