Development Level

Tbio 16 | 11,651
Tdark 3 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased bone mineral content 2 | 151
preweaning lethality, complete... 2 | 979
abnormal maxilla morphology 1 | 17
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
increased circulating phosphat... 1 | 26
increased heart rate variabili... 1 | 7
increased total body fat amoun... 1 | 134
small seminal vesicle 1 | 10

Disease

Carcinoma 15 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
medulloblastoma, large-cell 10 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
glioblastoma 7 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
group 4 medulloblastoma 6 | 1,855
Pick disease 5 | 1,894
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
astrocytic glioma 4 | 2,597
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Breast cancer 3 | 3,578
Hepatomegaly 3 | 285
Intellectual disability 3 | 1,016
acute quadriplegic myopathy 3 | 1,158
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Autosomal recessive predisposition 2 | 1,442
Barth syndrome 2 | 23
Diabetes Mellitus, Experimental 2 | 108
Dull intelligence 2 | 645
Lipodystrophy 2 | 40
Liver Cirrhosis 2 | 181
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neutral lipid storage disease 2 | 12
Obesity 2 | 678
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Steatohepatitis 2 | 44
dermatomyositis 2 | 966
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abnormal pigmentation 1 | 25
Abnormality of blood and blood-forming tissues 1 | 10
Abnormality of the haematopoietic system 1 | 10
Acromegaly 1 | 51
Advanced bone age 1 | 35
Alopecia 1 | 115
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Brachydactyly 1 | 156
Broad feet 1 | 19
Chemical and Drug Induced Liver Injury 1 | 195
Class III malocclusion 1 | 78
Congenital small ears 1 | 48
Fatty liver disease 1 | 103
Generalized hirsutism 1 | 36
Heart conduction disease 1 | 83
Hematological Disease 1 | 18
Hirsutism 1 | 47
Hyperhidrosis disorder 1 | 81
Hyperinsulinism 1 | 133
Hypertrophic Cardiomyopathy 1 | 117
Hypertrophy of lower jaw 1 | 78
Ichthyosis 1 | 56
Increased size of mandible 1 | 78
Increased sweating 1 | 81
Insulin Resistance 1 | 72
Liver Cirrhosis, Experimental 1 | 769
Liver Failure 1 | 73
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mandibular hyperplasia 1 | 78
Melanoma 1 | 711
Methylmalonic acidemia 1 | 37
Muscle Weakness 1 | 170
Myopathy 1 | 185
Neurodegenerative Disorders 1 | 79
Osteoporosis 1 | 363
Pilocytic astrocytoma 1 | 56
Precocious Puberty 1 | 28
Sclerocystic Ovaries 1 | 17
Sensorineural Hearing Loss (disorder) 1 | 284
Sweating 1 | 81
Tall stature 1 | 34
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 20 | 4,145

PathwayCommons: humancyc Pathway

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