Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal gait 1 | 69
decreased body length 1 | 101
decreased lean body mass 1 | 135
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
increased body weight 1 | 25
increased lymphocyte cell numb... 1 | 32
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
Oculocerebrorenal syndrome 7 | 29
medulloblastoma, large-cell 7 | 6,241
Pick disease 6 | 1,894
osteosarcoma 6 | 7,950
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Intellectual disability 4 | 1,016
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Kidney cancer 3 | 2,613
Seizures 3 | 596
astrocytic glioma 3 | 2,597
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
Acquired scoliosis 2 | 281
Brachydactyly 2 | 156
Cataract 2 | 297
Cryptorchidism 2 | 296
Curvature of spine 2 | 282
Dent disease 2 | 18
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Epilepsy 2 | 792
Frontal bossing 2 | 157
Hypoplastic feet 2 | 66
Knee joint valgus deformity 2 | 56
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Aminoaciduria 1 | 38
Chronic Kidney Diseases 1 | 13
Clonus 1 | 18
Edema 1 | 81
Febrile Convulsions 1 | 14
Hooked clavicle 1 | 5
Hypercalciuria 1 | 27
Hyperkyphosis 1 | 111
Hypokalemia 1 | 52
Hypophonia 1 | 7
Hypoplastic toenails 1 | 22
Juvenile rheumatoid arthritis 1 | 111
Kyphosis deformity of spine 1 | 114
MUSCULAR DYSTROPHY, CONGENITAL, WITH CATARACTS AND INTELLECTUAL DISABILITY 1 | 1
Malignant neoplasm of skin 1 | 15
Metabolic Syndrome 1 | 20
Muscle Rigidity 1 | 49
Obsessive compulsive behavior 1 | 25
Pain 1 | 103
Platyspondyly 1 | 56
Postural instability 1 | 19
Progressive renal failure 1 | 13
Pyramidal sign 1 | 29
Reduced visual acuity 1 | 63
Renal glomerular disease 1 | 12
Resting Tremor 1 | 9
Retinopathy of prematurity 1 | 22
Self-Injurious Behavior 1 | 12
Serum cholesterol raised 1 | 22
Short hands 1 | 50
Short ribs 1 | 30
Shuffling, short-stepped gait 1 | 5
Skin Neoplasms 1 | 69
Sparse scalp hair 1 | 42
Spinocerebellar ataxia type 2 1 | 23
Supranuclear gaze palsy 1 | 6
Voice Fatigue 1 | 7

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 11 | 4,145
Non-IDG 2 | 12,091

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
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http://pathwaycommons.org/pc2/... 13 | 13
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http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
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http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
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http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptojanin-2 SYNJ2 Tbio Non-IDG -1.15573 16.3 157
Inositol polyphosphate 1-phosphatase INPP1 Tbio Enzyme -1.24647 18.1 100
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Type II inositol 1,4,5-trisphosphate 5-phosphatase INPP5B Tbio Enzyme -1.53163 29.3 109
Inositol monophosphatase 2 IMPA2 Tbio Enzyme -1.49842 31.5 67
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Inositol monophosphatase 1 IMPA1 Tclin Enzyme -2.34557 211.7 94
Phosphatidylinositide phosphatase SAC2 INPP5F Tbio Enzyme -0.71120 5.56 89
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.93536 10.1 92