Development Level

Tbio 16 | 11,445
Tchem 8 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal gait 2 | 69
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hypoactivity 1 | 132
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 20 | 11,493
osteosarcoma 14 | 7,950
glioblastoma 13 | 5,792
ependymoma 12 | 4,679
ovarian cancer 11 | 8,520
psoriasis 10 | 6,694
adult high grade glioma 9 | 3,801
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
lung carcinoma 8 | 2,843
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Schizophrenia 6 | 1,160
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Melanoma 5 | 711
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
Breast cancer 4 | 3,578
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
subependymal giant cell astrocytoma 4 | 2,287
Cancer 3 | 2,499
Skin cancer 3 | 469
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
Arthrogryposis 2 | 54
Chronic obstructive pulmonary disease 2 | 184
Essential Hypertension 2 | 94
Liver cancer 2 | 604
Liver disease 2 | 237
Pick disease 2 | 1,894
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
cystic fibrosis and chronic rhinosinusitis 2 | 214
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
Abnormality of nail of toe 1 | 11
Abnormality of the fingernails 1 | 51
Agammaglobulinemia 1 | 34
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Ankylosis 1 | 28
Asphyxiating thoracic dystrophy 1 | 44
Autosomal recessive congenital ichthyosis 4B 1 | 13
Blepharitis 1 | 23
Bronchiolitis 1 | 18
Cellulitis 1 | 20
Cellulitis of eyelid 1 | 17
Cherubism 1 | 13
Chromosome 1p36 deletion syndrome 1 | 23
Chronic kidney disease stage 5 1 | 31
Cryopyrin-Associated Periodic Syndromes 1 | 4
Decreased IgM 1 | 11
Edema 1 | 81
Erythema 1 | 58
Flushing 1 | 60
Focal segmental glomerulosclerosis 1 | 10
Hamman-Rich syndrome 1 | 34
Hemangiosarcoma 1 | 18
Hereditary spherocytosis type 1 1 | 23
Hypoplastic superior helix 1 | 4
Immunoglobulin A deficiency (disorder) 1 | 19
Inflammatory Bowel Diseases 1 | 35
Koilonychia 1 | 7
Leukonychia 1 | 6
Malocclusion 1 | 57
Multiple Endocrine Neoplasia Type 1 1 | 29
Nail disease 1 | 9
Nephrotic Syndrome 1 | 78
Nonorganic psychosis 1 | 84
Pain 1 | 103
Pneumonia, Interstitial 1 | 5
Poliomyelitis 1 | 14
Reflex sympathetic dystrophy 1 | 7
SPONDYLOCOSTAL DYSOSTOSIS 5 1 | 4
Seasonal affective disorder 1 | 28
Seizures, Focal 1 | 14
Severe Dengue 1 | 3
Townes-Brocks syndrome 1 | 15
Treacher Collins syndrome 1 | 27
Uveal melanoma 1 | 20
esophageal cancer 1 | 22
pancreatic ductal carcinoma 1 | 11

Tissue

Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393

Target Family

Enzyme 16 | 4,145
Kinase 9 | 634

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 68 | 68
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