Development Level

Tbio 4 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased grip strength 1 | 116
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
ovarian cancer 4 | 8,520
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Autosomal recessive predisposition 2 | 1,442
Epidemic typhus 2 | 6
Infantile onset 2 | 238
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
Amelogenesis imperfecta 1 | 29
Anemia 1 | 365
Atrophy of cerebellum 1 | 103
Autoimmune hepatitis 1 | 11
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Chronic Kidney Diseases 1 | 13
Clonus 1 | 18
Cognitive delay 1 | 608
Decreased platelet count 1 | 111
Degenerative brain disorder 1 | 100
Delayed myelination 1 | 22
Epilepsy 1 | 792
Failure to gain weight 1 | 365
Feeding difficulties 1 | 127
Global developmental delay 1 | 608
HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME 1 | 1
Hemoglobin low 1 | 124
Hepatitis C 1 | 94
Hyperechogenic kidneys 1 | 3
Hyperuricemia 1 | 49
Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome 1 | 1
Hypochloremic metabolic alkalosis 1 | 1
Hypomagnesemia 1 | 12
Hyponatremia 1 | 25
Hypoplasia of corpus callosum 1 | 90
Idiopathic pulmonary arterial hypertension 1 | 40
Infratentorial atrophy 1 | 103
Intellectual disability 1 | 1,016
Irritation - emotion 1 | 68
Leukopenia 1 | 72
Limb contractures 1 | 6
Liver disease 1 | 237
Mental and motor retardation 1 | 608
Multiple myeloma 1 | 1,332
Muscle hypotonia 1 | 571
Neurodegenerative disease 1 | 414
PONTOCEREBELLAR HYPOPLASIA, TYPE 2D 1 | 1
Pediatric failure to thrive 1 | 365
Periventricular white matter abnormalities 1 | 8
Polyuria 1 | 23
Pontocerebellar Hypoplasia Type 2 1 | 5
Pontocerebellar hypoplasia 1 | 36
Pontocerebellar hypoplasia type 2D 1 | 1
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Primary sclerosing cholangitis 1 | 14
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Progressive microcephaly 1 | 32
Progressive renal failure 1 | 13
Proteinuria 1 | 144
Pulmonary hypertension 1 | 85
Renal salt wasting 1 | 18
Respiratory Failure 1 | 104
Seizures 1 | 596
Severe acute respiratory syndrome 1 | 27
Sleep disturbances 1 | 37
Spastic Quadriplegia 1 | 42
Specific language impairment 1 | 34
Supratentorial atrophy 1 | 94
Thrombocytopenia 1 | 197
Type 2 fiber atrophy 1 | 8
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
diabetes mellitus 1 | 1,728
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
medulloblastoma, large-cell 1 | 6,241
non primary Sjogren syndrome sicca 1 | 891
non-inflammatory breast cancer 1 | 66
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
pulmonary arterial hypertension 1 | 75
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 5 | 4,145
Kinase 1 | 634

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
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http://pathwaycommons.org/pc2/... 25 | 25
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http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Selenide, water dikinase 2 SEPHS2 Tdark Enzyme -1.42671 25.3 0
O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS Tbio Enzyme -2.11362 120.5 120
L-seryl-tRNA(Sec) kinase PSTK Tdark Kinase -1.27559 18.1 37
Selenide, water dikinase 1 SEPHS1 Tbio Enzyme -1.73899 51.6 124
Serine--tRNA ligase, mitochondrial SARS2 Tbio Enzyme -2.55777 0.00000 95
Serine--tRNA ligase, cytoplasmic SARS Tbio Enzyme -2.37540 230.1 178