Development Level

Tbio 10 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased lymphocyte cell numb... 1 | 32
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39

Disease

Carcinoma 12 | 11,493
osteosarcoma 9 | 7,950
medulloblastoma, large-cell 8 | 6,241
Oculocerebrorenal syndrome 7 | 29
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
lung cancer 7 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
lung carcinoma 6 | 2,843
ovarian cancer 6 | 8,520
Astrocytoma, Pilocytic 5 | 3,081
Pick disease 5 | 1,894
primitive neuroectodermal tumor 5 | 3,035
astrocytoma 4 | 1,146
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Intellectual disability 3 | 1,016
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Cryptorchidism 2 | 296
Curvature of spine 2 | 282
Dent disease 2 | 18
Down syndrome 2 | 499
Dull intelligence 2 | 645
Epilepsy 2 | 792
Frontal bossing 2 | 157
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Seizures 2 | 596
active Crohn's disease 2 | 922
atypical teratoid/rhabdoid tumor 2 | 357
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
group 4 medulloblastoma 2 | 1,855
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Adult Fanconi syndrome 1 | 12
Aminoaciduria 1 | 38
Chronic Kidney Diseases 1 | 13
Clonus 1 | 18
Defective enamel matrix 1 | 35
Dehydration 1 | 40
Dental Enamel Hypoplasia 1 | 43
Dysphasia 1 | 23
Dysplasia of tooth enamel 1 | 35
Edema 1 | 81
Generalized hypopigmentation 1 | 12
Hooked clavicle 1 | 5
Hypercalciuria 1 | 27
Hyperkyphosis 1 | 111
Hyperphosphaturia 1 | 21
Hypokalemia 1 | 52
Hypophonia 1 | 7
Hypoplastic ilia 1 | 12
Hypoplastic ischia 1 | 11
Hypoplastic pubic bone 1 | 7
Hypoplastic toenails 1 | 22
Kyphosis deformity of spine 1 | 114
MUSCULAR DYSTROPHY, CONGENITAL, WITH CATARACTS AND INTELLECTUAL DISABILITY 1 | 1
Malignant neoplasm of skin 1 | 15
Metabolic Syndrome 1 | 20
Muscle Rigidity 1 | 49
Obsessive compulsive behavior 1 | 25
Platyspondyly 1 | 56
Pneumocystosis 1 | 17
Postural instability 1 | 19
Progressive renal failure 1 | 13
Pyramidal sign 1 | 29
Reduced visual acuity 1 | 63
Renal glomerular disease 1 | 12
Resting Tremor 1 | 9
Retinopathy of prematurity 1 | 22
Self-Injurious Behavior 1 | 12
Serum cholesterol raised 1 | 22
Short hands 1 | 50
Short ribs 1 | 30
Shuffling, short-stepped gait 1 | 5
Skin Neoplasms 1 | 69
Small wings of the pelvic girdle 1 | 12
Sparse scalp hair 1 | 42
Spinocerebellar ataxia type 2 1 | 23
Supranuclear gaze palsy 1 | 6
Thin dental enamel 1 | 35
Urine phosphorous concentration above normal 1 | 21
Voice Fatigue 1 | 7

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 14 | 16,678

Target Family

Enzyme 8 | 4,145
Kinase 5 | 634
Non-IDG 2 | 12,091

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 25 | 25
http://pathwaycommons.org/pc2/... 23 | 23
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 15 | 15
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 14 | 14
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 13 | 13
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 12 | 12
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 11 | 11
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 10 | 10
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 9 | 9
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 8 | 8
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 6 | 6
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http://pathwaycommons.org/pc2/... 6 | 6
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http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 6 | 6
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
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http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5
http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptojanin-2 SYNJ2 Tbio Non-IDG -1.15573 16.3 157
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Inositol polyphosphate multikinase IPMK Tbio Kinase -1.55144 39.0 159
Inositol-trisphosphate 3-kinase B ITPKB Tchem Kinase -1.44569 29.5 168
Inositol-trisphosphate 3-kinase A ITPKA Tchem Kinase -1.42824 28.0 156
Type II inositol 1,4,5-trisphosphate 5-phosphatase INPP5B Tbio Enzyme -1.53163 29.3 109
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 INPP5D Tbio Enzyme -2.06945 104.7 374
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
Inositol-tetrakisphosphate 1-kinase ITPK1 Tbio Kinase -1.38434 24.8 201