Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

Disease

ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Multiple myeloma 2 | 1,332
Neuropathy 2 | 261
aldosterone-producing adenoma 2 | 665
atypical teratoid / rhabdoid tumor 2 | 5,112
facioscapulohumeral dystrophy 2 | 288
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
tuberculosis 2 | 2,010
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alopecia universalis 1 | 16
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Atopic dermatitis 1 | 952
Autoamputation 1 | 2
Autoamputation of foot 1 | 2
Autosomal recessive congenital ichthyosis 4B 1 | 13
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Chronic axonal neuropathy 1 | 2
Congenital pes cavus 1 | 88
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Decreased tendon reflex 1 | 122
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Down syndrome 1 | 499
Dysesthesia 1 | 6
Foot Deformities 1 | 30
Heart disease 1 | 306
Hereditary sensory and autonomic neuropathy type IC 1 | 1
Hereditary sensory neuropathy 1 | 11
Infection of bone 1 | 19
Lipid storage disease 1 | 8
Lumbosacral lipoma 1 | 3
Lymphoma, Follicular 1 | 18
Multiple Sclerosis 1 | 540
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IA 1 | 1
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IC 1 | 1
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy, Hereditary Sensory and Autonomic, Type 1A 1 | 1
Osteomyelitis 1 | 42
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Palmoplantar keratosis 1 | 74
Peripheral sensorimotor neuropathy 1 | 16
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Skeletal muscle atrophy 1 | 139
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Tabes dorsalis 1 | 6
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 459
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 6 months 1 | 409
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 5 | 4,145

PathwayCommons: humancyc Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203
Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 DEGS2 Tbio Enzyme -1.71761 46.1 74
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24
3-ketodihydrosphingosine reductase KDSR Tbio Enzyme -1.21646 15.3 101