Development Level

Tbio 3 | 11,445

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
enlarged heart 1 | 210
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Atopic dermatitis 2 | 952
Sjogren-Larsson syndrome 2 | 6
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Abnormal skeletal development 1 | 60
Abnormality of retinal pigmentation 1 | 111
Aceruloplasminemia 1 | 16
Angiokeratoma 1 | 9
Autosomal recessive predisposition 1 | 1,442
Beriberi 1 | 12
Central nervous system demyelination 1 | 28
Cerebral palsy 1 | 40
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis 1 | 155
Chronic Lymphocytic Leukemia 1 | 262
Corneal erosion 1 | 16
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Dry skin 1 | 75
Dysarthria 1 | 192
Dysplasia of tooth enamel 1 | 35
Dystonia 1 | 164
Epilepsy 1 | 792
Erythema 1 | 58
Flushing 1 | 60
Gaucher disease type 1 1 | 180
Generalized hyperpigmentation 1 | 22
Hemangiopericytoma 1 | 5
Hereditary spastic paraplegia 35 1 | 5
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Inflammatory abnormality of the eye 1 | 10
Kyphosis deformity of spine 1 | 114
Leukodystrophy 1 | 55
Leukodystrophy, Dysmyelinating, And Spastic Paraparesis With Or Without Dystonia 1 | 1
Little's Disease 1 | 14
Macular degeneration 1 | 65
Muscle Spasticity 1 | 195
Myopia 1 | 176
Neuroaxonal dystrophy 1 | 8
Neurodegeneration with brain iron accumulation 1 | 20
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Neutral lipid storage disease 1 | 12
Osteochondrodysplasias 1 | 72
Osteogenesis imperfecta type 2 1 | 8
Paraplegia 1 | 74
Peroxisomal disease 1 | 22
Photodysphoria 1 | 121
Photophobia 1 | 121
Pick disease 1 | 1,894
Pyramidal sign 1 | 29
Quadriplegia 1 | 20
Refsum disease 1 | 20
Retinal Diseases 1 | 55
Retinal pigment epithelial abnormality 1 | 111
Rhizomelic chondrodysplasia punctata 1 | 11
Seizures 1 | 596
Sengers syndrome 1 | 18
Sj??gren-Larsson syndrome 1 | 1
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Superficial corneal opacities 1 | 1
Thin dental enamel 1 | 35
Thoracic kyphosis 1 | 6
X-linked cerebral adrenoleukodystrophy 1 | 116
Xerosis 1 | 75
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
gastric carcinoma 1 | 807
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung cancer 1 | 4,740
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
posterior fossa group B ependymoma 1 | 416
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
progressive supranuclear palsy 1 | 676
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

PathwayCommons: humancyc Pathway

http://pathwaycommons.org/pc2/... 3 | 3
http://pathwaycommons.org/pc2/... 68 | 68
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 27 | 27
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http://pathwaycommons.org/pc2/... 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2-hydroxyacyl-CoA lyase 1 HACL1 Tbio Enzyme -1.82472 63.8 159
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Fatty acid 2-hydroxylase FA2H Tbio Enzyme -2.48916 293.9 133